Buysschaert M, Ketelslegers J M, Mpoy M, Galanti L, Pirson F, Pouthier F, Lambert A E
Cliniques Universitaires de Mont-Godinne, Belgium.
Diabetes Res. 1987 Nov;6(3):129-31.
Serum fructosamine was determined in 115 diabetic patients with a C-Peptide secretion (0.84 +/- 0.06 pmol/ml, mean +/- SEM) (Group A) and in 30 type I C-peptide negative totally insulin-dependent subjects (less than 0.05 pmol/ml) (Group B). A significant correlation between fructosamine and HbA1 values (r = 0.70, p less than 0.001) was evidenced in Group A. In contrast, such a correlation was not found in Group B (r = 0.33, p greater than 0.05). Fructosamine levels were also in good agreement with the physician's ratings of the degree of glycemic control in Group A, but not in Group B. It is concluded that the fructosamine measurement represents a complement rather than an alternative to HbA1, in particular in unstable diabetic patients.
对115例C肽分泌量为（0.84±0.06皮摩尔/毫升，均值±标准误）的糖尿病患者（A组）和30例I型C肽阴性的完全胰岛素依赖型受试者（低于0.05皮摩尔/毫升）（B组）测定了血清果糖胺。A组中果糖胺与糖化血红蛋白（HbA1）值之间存在显著相关性（r = 0.70，p<0.001）。相比之下，B组未发现这种相关性（r = 0.33，p>0.05）。A组中果糖胺水平也与医生对血糖控制程度的评分高度一致，但B组并非如此。得出的结论是，果糖胺测量是对HbA1的补充而非替代，特别是在不稳定的糖尿病患者中。
