过渡金属催化异腈与三芳基铋试剂的双芳基化反应用于亚胺衍生物的选择性合成
Transition-Metal-Catalyzed Diarylation of Isocyanides with Triarylbismuthines for the Selective Synthesis of Imine Derivatives.
作者信息
Kodama Shintaro, Yamamoto Yuki, Kobiki Yohsuke, Matsubara Hitomi, Tran Cong Chi, Kawaguchi Shin-Ichi, Nomoto Akihiro, Ogawa Akiya
机构信息
Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, 1-1 Gakuen-cho, Nakaku, Sakai, Osaka 599-8531, Japan.
Center for Education and Research in Agricultural Innovation, Faculty of Agriculture, Saga University, 152-1 Shonan-cho, Karatsu, Saga 847-0021, Japan.
出版信息
Materials (Basel). 2021 Jul 30;14(15):4271. doi: 10.3390/ma14154271.
The transition-metal-catalyzed diarylation of isocyanides with triarylbismuthines was investigated in detail, and rhodium catalysts such as [RhCl(nbd)] were found to selectively afford -alkyl diaryl ketimines. On the other hand, palladium-catalyzed diarylation proceeded with the incorporation of two molecules of isocyanide, preferentially yielding ,-dialkyl or ,-diaryl -diimines. In addition, a cascade synthesis of 2,3-diarylquinoxalines starting from the palladium-catalyzed diarylation of isocyanides with triarylbismuthines was successfully achieved.
对过渡金属催化异腈与三芳基铋的二芳基化反应进行了详细研究，发现铑催化剂如[RhCl(nbd)]能选择性地生成α-烷基二芳基酮亚胺。另一方面，钯催化的二芳基化反应伴随着两分子异腈的引入，优先生成α,β-二烷基或α,β-二芳基二亚胺。此外，从钯催化异腈与三芳基铋的二芳基化反应出发，成功实现了2,3-二芳基喹喔啉的串联合成。
Zotero 插件