Kamissoko Aly Badra, Eloundou Paul, Traoré Marie, Diallo Mamadou Lamine, Mendo Gervais, Diallo M'balou Fatoumata, Diallo Alhassane
Service de Rhumatologie, Hôpital National Ignace Deen, Conakry, Guinée.
Service de Médecine Interne Hôpital de District d´Efoulan, Yaoundé, Cameroun.
Pan Afr Med J. 2021 Apr 19;38:379. doi: 10.11604/pamj.2021.38.379.20098. eCollection 2021.
rheumatoid arthritis (RA) dramatically affects the quality of life of patients. The objective of our study was to study the link between the activity of the disease and the quality of life of Guinean (Conakry) and Cameroonian patients with RA.
pilot multicentric cross-sectional study (Ignace Dean National Hospital of Conakry in Guinea and Efoulan Yaoundé District Hospital in Cameroon) for 15 months (1 October 2016 to 30 January 2018). The diagnosis of RA was based on the criteria of the ACR/EULAR. Disease activity was assessed by DAS 28. The EMIR questionnaire and the Steinbrocker score were used to assess quality of life.
fifty-two patients, 82% of whom were women. The total EMIR score was 5.06±0.50 as a relatively impaired quality of life. Alteration of quality of life was more marked on psychic components (6.78±0.99) and pain (5.37±0.99). The work component was the least affected (4.03±0.98). DAS28 was significantly related to psychic components (p=0.036, R=0.29), pain (p=0.076, R=0.25), physical (p=0.0029, R=0.41), and at the overall quality of life (total EMIR) (p=0.027, R=0.31).
the most significant of RA on quality of life was related to pain (EVA-pain) and RA activity (DAS 28). The results of this pilot study will have to be confirmed by a largest study.
类风湿性关节炎（RA）严重影响患者的生活质量。我们研究的目的是探讨几内亚（科纳克里）和喀麦隆RA患者的疾病活动与生活质量之间的联系。
在几内亚科纳克里的伊尼亚斯·迪恩国家医院和喀麦隆雅温得埃富兰区医院进行了为期15个月（2016年10月1日至2018年1月31日）的多中心横断面试点研究。RA的诊断基于美国风湿病学会/欧洲抗风湿病联盟（ACR/EULAR）的标准。通过DAS 28评估疾病活动度。使用EMIR问卷和斯坦布鲁克评分来评估生活质量。
52例患者，其中82%为女性。EMIR总评分为5.06±0.50，生活质量相对受损。生活质量的改变在心理成分（6.78±0.99）和疼痛（5.37±0.99）方面更为明显。工作成分受影响最小（4.03±0.98）。DAS28与心理成分（p = 0.036，R = 0.29）、疼痛（p = 0.076，R = 0.25）、身体状况（p = 0.0029，R = 0.41）以及总体生活质量（EMIR总分）（p = 0.027，R = 0.31）显著相关。
RA对生活质量的最显著影响与疼痛（视觉模拟评分法疼痛）和RA活动度（DAS 28）有关。这项试点研究的结果必须通过更大规模的研究来证实。
