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国家加速创新中心的流程、进展及成果概述:波士顿生物医学创新中心的经验

An overview of the process, progress, and outcomes of a National Center for Accelerated Innovation: The Boston Biomedical Innovation Center Experience.

作者信息

Antman Elliott M, Freeman Mason W, Golan David E, Kitterman Roger, McKenna Erin, Parrish John, Vaughan Cheryl, Watts Lesley, Loscalzo Joseph

机构信息

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

出版信息

J Clin Transl Sci. 2021 May 17;5(1):e137. doi: 10.1017/cts.2021.791. eCollection 2021.

DOI:10.1017/cts.2021.791
PMID:34367681
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8327551/
Abstract

Implementation of clinically useful research discoveries in the academic environment is challenged by limited funding for early phase proof-of-concept studies and inadequate expertise in product development and commercialization. To address these limitations, the National Institutes of Health (NIH) established the National Centers for Accelerated Innovations (NCAI) program in 2013. Three centers competed successfully for awards through this mechanism. Here, we present the experience of one such center, the Boston Biomedical Innovation Center (B-BIC), and demonstrate its remarkable success at the translation of innovations to clinical application and commercialization, as well as skills development and education.

摘要

在学术环境中,将具有临床实用价值的研究成果转化为实际应用面临着诸多挑战,其中包括早期概念验证研究的资金有限,以及产品开发和商业化方面的专业知识不足。为应对这些限制,美国国立卫生研究院(NIH)于2013年设立了国家加速创新中心(NCAI)计划。有三个中心通过这一机制成功获得了奖项。在此,我们介绍其中一个中心——波士顿生物医学创新中心(B-BIC)的经验,并展示其在将创新成果转化为临床应用和商业化,以及技能培养和教育方面取得的显著成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/a127c8aa5ff1/S2059866121007913_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/859c3acf3422/S2059866121007913_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/46703f2c0308/S2059866121007913_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/c68ac75fe4fc/S2059866121007913_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/a127c8aa5ff1/S2059866121007913_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/859c3acf3422/S2059866121007913_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/46703f2c0308/S2059866121007913_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/c68ac75fe4fc/S2059866121007913_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a13/8327551/a127c8aa5ff1/S2059866121007913_fig4.jpg

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本文引用的文献

1
NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges.NIH 加速创新计划:原则、实践、成功与挑战。
Nat Rev Drug Discov. 2017 Oct;16(10):663-664. doi: 10.1038/nrd.2017.131. Epub 2017 Aug 4.