Khan Muhammad Atique Alam, Minalyan Artem, Iqbal Iqra
Internal Medicine, Abington Hospital-Jefferson Health, Abington, USA.
Cureus. 2021 Jul 2;13(7):e16114. doi: 10.7759/cureus.16114. eCollection 2021 Jul.
Hypokalemia is a relatively common electrolyte abnormality in hospitalized patients. Severe hypokalemia (<2.5 mEq/L) can lead to profound muscle weakness or paralysis, especially in the setting of acute onset of hypokalemia. Multiple mechanisms of hypokalemia have been described, such as decreased potassium intake, increased losses, and increased transcellular shift of potassium. Drugs can rarely cause hypokalemia by one of the above-mentioned mechanisms. Here, we report a case of cocaine use leading to severe hypokalemia manifesting as quadriparesis. The aggressive repletion of potassium led to a complete resolution of muscular weakness.
低钾血症是住院患者中相对常见的电解质异常。严重低钾血症(<2.5 mEq/L)可导致严重的肌肉无力或麻痹,尤其是在低钾血症急性发作的情况下。低钾血症的多种机制已被描述,如钾摄入减少、丢失增加和钾的跨细胞转移增加。药物很少通过上述机制之一导致低钾血症。在此,我们报告一例因使用可卡因导致严重低钾血症并表现为四肢瘫的病例。积极补钾使肌肉无力完全缓解。