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基于2015 - 2019年加利福尼亚州药品使用回顾与评价系统(CURES)数据报告评估儿科和年轻人中的阿片类药物配药率。

Evaluating Opioid Dispensing Rates among Pediatrics and Young Adults based on CURES Data Reporting in California from 2015-2019.

作者信息

Phan Michael T, Wong Courtney, Tomaszewski Daniel M, Kain Zeev N, Jenkins Brooke, Donaldson Candice, Fortier Michelle, Yang Sun

机构信息

Chapman University School of Pharmacy.

Department of Pharmaceutical and Health Economics at the University of Southern California's School of Pharmacy.

出版信息

J Contemp Pharm Prac. 2021;67(4):23-32. doi: 10.37901/jcphp20-00012. Epub 2021 Mar 3.

DOI:10.37901/jcphp20-00012
PMID:34368640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8341537/
Abstract

BACKGROUND

Receipt of opioid prescriptions in pediatric and young adult patients may be a risk factor for future opioid misuse. Data from prescription drug monitoring programs provide insight on outpatient opioid use. In our study, we analyzed the opioid dispensing rates for pediatrics and young adults in California.

METHODS

A secondary analysis was performed from 2015-2019 using Controlled Utilization Review and Evaluation System data. This database provides dispensing data of controlled substances in California. Patients younger than 25 years who were prescribed opiates were analyzed by county. We further divided them into two groups (children: ≤14 years; adolescents and young adult: 15-24 years). Descriptive statistics and heat maps were used to illustrate the trends in opioid usage among different age groups.

RESULTS

The overall percentages for the number of opioids being dispensed to patients aged <25 years have decreased over the past four years. In 2015, 6 out of 58 counties in California were considered "high-rate" with >2.9% of opioids dispensed to patients younger than 25 years old; in 2019, this number reduced to zero. Patients 25 and older received a higher proportion of opioids compared to younger populations; in 2019, 35.91% of opioids were dispensed to patients 45-64, and 8.92% to patients younger than 25.

CONCLUSION

Pediatric opioid prescriptions have declined over the recent years. However, a high degree of variability of prescription rates between demographic counties was noted. More studies are warranted in order to understand this discrepancy in opioid prescribing among pediatric and young adult patients.

摘要

背景

儿科和年轻成年患者开具阿片类药物处方可能是未来阿片类药物滥用的一个风险因素。处方药监测计划的数据提供了关于门诊阿片类药物使用情况的见解。在我们的研究中,我们分析了加利福尼亚州儿科和年轻成年人的阿片类药物配药率。

方法

利用2015年至2019年的受控利用审查和评估系统数据进行了二次分析。该数据库提供了加利福尼亚州受控物质的配药数据。对开具阿片类药物处方的25岁以下患者按县进行分析。我们进一步将他们分为两组(儿童:≤14岁;青少年和年轻成年人:15 - 24岁)。使用描述性统计和热图来说明不同年龄组阿片类药物使用的趋势。

结果

在过去四年中,向25岁以下患者配给的阿片类药物数量的总体百分比有所下降。2015年,加利福尼亚州58个县中有6个被视为“高比率”,即向25岁以下患者配给的阿片类药物超过2.9%;到2019年,这个数字降至零。25岁及以上患者比年轻人群体获得的阿片类药物比例更高;2019年,35.91%的阿片类药物配给了45 - 64岁的患者,8.92%配给了25岁以下的患者。

结论

近年来儿科阿片类药物处方有所下降。然而,不同人口统计学县之间的处方率存在高度差异。为了了解儿科和年轻成年患者阿片类药物处方的这种差异,需要进行更多的研究。

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