Department of Social Sciences and Health Policy and CTSI Program in Community-Engaged Research, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Northwestern University, Department of Pediatrics, Feinberg School of Medicine, and the Ann & Robert H. Lurie Children's Hospital of Chicago, Potocsnak Family Division of Adolescent and Young Adult Medicine, Chicago, Illinois.
AIDS Educ Prev. 2021 Aug;33(4):345-360. doi: 10.1521/aeap.2021.33.4.345.
In the United States, transgender women are disproportionately affected by HIV. However, few evidence-based prevention interventions exist for this key population. We describe two promising, locally developed interventions that are currently being implemented and evaluated through the Centers for Disease Control and Prevention Combination HIV Prevention for Transgender Women Project: (a) ChiCAS, designed to promote the uptake of pre-exposure prophylaxis (PrEP), condom use, and medically supervised hormone therapy among Spanish-speaking transgender Latinas, and (b) TransLife Care, designed to address the structural drivers of HIV risk through access to housing, employment, legal services, and medical services, including HIV preventive care (e.g., PrEP use) among racially/ethnically diverse urban transgender women. If the evaluation trials determine that these interventions are effective, they will be among the first such interventions for use with transgender women incorporating PrEP, thereby contributing to the evidence-based resources that may be used to reduce HIV risk among this population.
在美国，跨性别女性受 HIV 影响的比例不成比例。然而，针对这一关键人群的循证预防干预措施很少。我们描述了两种有前途的、本土化开发的干预措施，目前正在通过疾病预防控制中心组合 HIV 预防跨性别女性项目进行实施和评估：（a）ChiCAS，旨在促进讲西班牙语的跨性别拉丁裔女性采用暴露前预防（PrEP）、使用避孕套和医学监督下的激素治疗；（b）TransLife Care，旨在通过获得住房、就业、法律服务和医疗服务来解决 HIV 风险的结构性驱动因素，包括为不同种族/族裔的城市跨性别女性提供 HIV 预防护理（例如 PrEP 的使用）。如果评估试验确定这些干预措施有效，它们将成为首批将 PrEP 纳入使用的针对跨性别女性的干预措施之一，从而为可能用于降低该人群 HIV 风险的循证资源做出贡献。
