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“光调节转录组动力学,上调雨生红球藻中虾青素的积累:综述”。

"Light modulates transcriptomic dynamics upregulating astaxanthin accumulation in Haematococcus: A review".

机构信息

Diatom Nanoengineering and Metabolism Laboratory (DNM), School of Applied science, Dr. Harisingh Gour Central University, Sagar, MP 470003, India; Metabolism, Engineering of Microalgal Molecules and Applications (MIMMA), Mer Molecules Santé, Molecules & Health (EA 2160), Le Mans University, IUML - FR 3473 CNRS, Le Mans, France.

Diatom Nanoengineering and Metabolism Laboratory (DNM), School of Applied science, Dr. Harisingh Gour Central University, Sagar, MP 470003, India.

出版信息

Bioresour Technol. 2021 Nov;340:125707. doi: 10.1016/j.biortech.2021.125707. Epub 2021 Aug 3.

Abstract

Haematococcus pluvialis is a green alga that can accumulate high astaxanthin content, a commercially demanding market keto food. Due to its high predicted market value of about 3.4 billion USD in 2027, it is essential to increase its production. Therefore, it is crucial to understand the genetic mechanism and gene expressions profile during astaxanthin synthesis. The effect of poly- and mono-chromatic light of different wavelengths and different intensities have shown to influence the gene expression towards astaxanthin production. This includes transcriptomic gene analysis in H. pluvialis underneath different levels of illumination stress. This review has placed the most recent data on the effects of light on bioastaxanthin production in the context of previous studies, which were more focused on the biochemical and physiological sides. Doing so, it contributes to delineate new ways along the biotechnological process with the aim to increase bioastaxanthin production while decreasing production costs.

摘要

雨生红球藻是一种绿藻,能够积累高含量的虾青素,这是一种市场需求旺盛的类胡萝卜素。由于其在 2027 年的预测市场价值高达 34 亿美元,因此提高其产量至关重要。因此,了解虾青素合成过程中的遗传机制和基因表达谱至关重要。不同波长和强度的多色和单色光的影响已经表明会影响基因表达,从而促进虾青素的产生。这包括在不同光照胁迫水平下对 H. pluvialis 进行转录组基因分析。本综述将最新的数据放在光对生物虾青素生产的影响方面,这与之前更侧重于生物化学和生理学方面的研究不同。这样做有助于为生物技术过程开辟新途径,旨在提高生物虾青素的产量,同时降低生产成本。

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