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法国长期护理机构居民的 2019 年冠状病毒病首剂疫苗接种覆盖率。

First-Dose Coronavirus 2019 Vaccination Coverage among the Residents of Long-Term Care Facilities in France.

机构信息

Hôpital Charles Foix, Assistance Publique-Hôpitaux de Paris, Ivry-sur-Seine, France.

Faculté de médecine, Sorbonne Université, Paris, France.

出版信息

Gerontology. 2022;68(5):546-550. doi: 10.1159/000517793. Epub 2021 Aug 11.

DOI:10.1159/000517793
PMID:34380133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8450844/
Abstract

BACKGROUND

Long-term care facilities (LTCFs) experienced severe burden from the Coronavirus 2019 (COVID-19), and vaccination against SARS-CoV-2 is a major issue for their residents.

OBJECTIVE

The objective of this study was to estimate the vaccination coverage rate among the residents of French LTCFs.

METHOD

Participants and settings: 53 medical coordinators surveyed 73 LTCFs during the first-dose vaccination campaign using the BNT162b2 vaccine, conducted by health authorities in January and early February 2021.

MEASUREMENTS

in all the residents being in the LTCF at the beginning of the campaign, investigators recorded age, sex, history of clinical or asymptomatic COVID-19, serology for SARS-CoV-2 or severe allergy, current end-of-life situation, infectious or acute disease, refusal of vaccination by the resident or by the representative person of vaccine, and the final status, vaccinated or not.

RESULTS

Among the 4,808 residents, the average coverage rate for COVID-19 vaccination was 69%, and 46% of the LTCFs had a coverage rate <70%. Among unvaccinated residents, we observed more frequently a history of COVID-19 or a positive serology for SARS-CoV-2 (44.6 vs. 11.2% among vaccinated residents, p < 0.001), a history of severe allergy (3.7 vs. 0.1%, p < 0.001), end-of-life situation (4.9 vs. 0.3%, p < 0.001), current infectious or acute illness (19.6 vs. 0.3%, p < 0.001), and refusal of vaccination by residents or representative persons (38.9 vs. 0.4%, p < 0.001).

CONCLUSIONS

About 3 out of 10 residents remained unvaccinated, and half of the LTCFs had a coverage rate <70%. This suggests that COVID-19 will remain a threat to many LTCFs after the vaccination campaigns.

摘要

背景

长期护理机构(LTCF)在 2019 年冠状病毒病(COVID-19)期间承受了巨大的负担,对 SARS-CoV-2 的疫苗接种是其居民的一个主要问题。

目的

本研究旨在估计法国 LTCF 居民的疫苗接种覆盖率。

方法

参与者和设置:2021 年 1 月和 2 月初,卫生当局进行了 BNT162b2 疫苗的第一剂疫苗接种运动,53 名医疗协调员调查了 73 个 LTCF。

测量

在运动开始时,调查人员记录了所有在 LTCF 中的居民的年龄、性别、临床或无症状 COVID-19 病史、SARS-CoV-2 血清学或严重过敏、当前临终状况、传染病或急性疾病、居民或疫苗代表人拒绝接种疫苗,以及最终状态,接种或未接种。

结果

在 4808 名居民中,COVID-19 疫苗接种的平均覆盖率为 69%,46%的 LTCF 覆盖率<70%。在未接种疫苗的居民中,我们更频繁地观察到 COVID-19 病史或 SARS-CoV-2 血清学阳性(44.6%比接种疫苗的居民 11.2%,p<0.001)、严重过敏史(3.7%比 0.1%,p<0.001)、临终状况(4.9%比 0.3%,p<0.001)、当前传染病或急性疾病(19.6%比 0.3%,p<0.001)以及居民或代表人拒绝接种疫苗(38.9%比 0.4%,p<0.001)。

结论

大约 3 成的居民仍未接种疫苗,一半的 LTCF 覆盖率<70%。这表明,COVID-19 在疫苗接种运动后仍将对许多 LTCF 构成威胁。

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