Mandura Rahaf A, Alqahtani Abdullah S
Department of Ophthalmology, King Abdulaziz University, Jeddah, SAU.
Department of Ophthalmology, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Jeddah, SAU.
Cureus. 2021 Jul 10;13(7):e16303. doi: 10.7759/cureus.16303. eCollection 2021 Jul.
Coats' disease is an idiopathic non-hereditary condition first described by Coats in 1908 as a congenital retinal telangiectatic and aneurysmal disease associated with retinal exudation. Its presentation is classically in early childhood. We report a rare case of Coats' disease that first presented during adulthood in a 35-year-old male. The patient presented with visual loss in the left eye for two months. His visual acuity was counting fingers in the left eye and fundus examination revealed extensive lipid exudation in the macula with telangiectatic vessels and microaneurysms with vascular malformation in the inferotemporal quadrant. Fluorescein angiography showed leakage from the telangiectatic vessels, and optic coherence tomography showed significant macular edema. A provisional diagnosis of adult-onset Coats' disease was made. The patient responded well to intravitreal ranibizumab injections for macular edema and sectoral argon laser photocoagulation for peripheral vascular abnormalities. This case is unusual in adulthood onset and the first presentation was during adulthood in the third decade of life in contrast to the typical age of onset which is younger than five years.
科茨病是一种特发性非遗传性疾病,1908年由科茨首次描述为一种与视网膜渗出相关的先天性视网膜毛细血管扩张和动脉瘤性疾病。其典型表现为儿童早期发病。我们报告一例罕见的科茨病病例,首次发病于一名35岁男性的成年期。患者因左眼视力下降两个月前来就诊。其左眼视力为眼前数指,眼底检查显示黄斑区有广泛的脂质渗出,伴有毛细血管扩张血管和微动脉瘤,颞下象限有血管畸形。荧光素血管造影显示毛细血管扩张血管渗漏,光学相干断层扫描显示黄斑区明显水肿。初步诊断为成人型科茨病。患者接受玻璃体内注射雷珠单抗治疗黄斑水肿,以及对周边血管异常进行扇形氩激光光凝治疗后,反应良好。该病例成年发病情况不常见,首次发病于30岁的成年期,与典型发病年龄小于5岁形成对比。