Kumar Kshitiz, Raj Pallavi, Chandnani Nisha, Agarwal Amar
Dr. Agarwal's Eye Hospital, Kolkata, India.
Dr. Agarwal's Eye Hospital, Chennai, India.
Int Ophthalmol. 2019 Feb;39(2):465-470. doi: 10.1007/s10792-018-0827-0. Epub 2018 Jan 29.
To report a case of adult-onset Coats' disease with secondary retinal vasoproliferative tumor managed with dexamethasone intravitreal implant and retinal photocoagulation.
Case study.
A 41-year-old female with counting finger vision was diagnosed with Coats' disease with secondary retinal vasoproliferative tumor in right eye. Fundus examination revealed exudative retinopathy involving posterior pole and a retinal tumor located in the inferotemporal quadrant. Optical coherence tomography scan confirmed massive exudative neurosensory detachment and fundus fluorescein angiography showed areas of telangiectatic vessels with capillary non-perfusion. Intravitreal injection of dexamethasone implant was done initially followed by laser photocoagulation when the detachment resolved. There was significant improvement in patient's visual acuity with no further recurrence of exudation.
Intravitreal dexamethasone implant Ozurdex() (Allergan, Inc., Irvine, Calif., USA) may be an effective initial therapeutic approach for Coats' disease with massive exudation.
报告一例成人发病的科茨病合并继发性视网膜血管增生性肿瘤，采用地塞米松玻璃体内植入联合视网膜光凝治疗的病例。
病例研究。
一名41岁女性，右眼视力为指数，被诊断为科茨病合并继发性视网膜血管增生性肿瘤。眼底检查发现累及后极部的渗出性视网膜病变以及位于颞下象限的视网膜肿瘤。光学相干断层扫描证实存在大量渗出性神经感觉性脱离，眼底荧光血管造影显示有毛细血管无灌注的扩张血管区域。最初进行了玻璃体内注射地塞米松植入物，当脱离缓解后进行了激光光凝。患者视力有显著改善，渗出未再复发。
玻璃体内注射地塞米松植入物Ozurdex（美国加利福尼亚州欧文市艾尔建公司）可能是治疗伴有大量渗出的科茨病的一种有效的初始治疗方法。
