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[Role of 131I-metaiodobenzylguanidine scintigraphy in the diagnosis of intestinal carcinoids].

作者信息

Bihl H, Sautter-Bihl M L, Wilhelm K R, Kimmig B

机构信息

Abteilung für Klin. Nuklearmedizin, Univ.-Strahlenklinik, Heidelberg, BRD.

出版信息

Nuklearmedizin. 1987 Dec;26(6):263-7.

PMID:3438170
Abstract

Iodine-131 metaiodobenzylguanidine (131I-MIBG) is concentrated in a variety of neuroendocrine tumors, such as pheochromocytoma and neuroblastoma. Other neuroendocrine tumors from the APUD-cell system such as carcinoid tumors, may possess this uptake capability as well. We investigated 11 patients suffering from intestinal carcinoid with 131I-MIBG in order to determine the value of MIBG scintigraphy in these tumors. MIBG scans were positive in 5 out of 11 patients (45%). False-positive MIBG-scans did not occur. No correlation between MIBG uptake, clinical symptoms and urinary 5-HIAA level could be found.

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