Feldman J M, Blinder R A, Lucas K J, Coleman R E
J Nucl Med. 1986 Nov;27(11):1691-6.
Iodine-131 metaiodobenzylguanidine ([131I]MIBG) is concentrated in pheochromocytomas and can be detected by external imaging. We administered [131I]MIBG to 23 patients with carcinoid tumors to determine if it would be useful in scanning patients with these tumors. The carcinoid tumors of 14 of the 23 patients (61%) were visualized. Iodine-131 MIBG was concentrated most avidly by tumors of midgut origin (ileum, cecum); it was concentrated less avidly by some tumors of foregut origin (pancreas, stomach); it was not significantly concentrated by other tumors of foregut origin (bronchus). We conclude that 131I is a useful imaging agent for carcinoid tumors.
碘-131间碘苄胍（[131I]MIBG）可在嗜铬细胞瘤中浓聚，并可通过体外显像检测到。我们对23例类癌患者给予[131I]MIBG，以确定其对这些肿瘤患者进行扫描是否有用。23例患者中有14例（61%）的类癌被显影。碘-131 MIBG在起源于中肠（回肠、盲肠）的肿瘤中浓聚最为明显；在一些起源于前肠（胰腺、胃）的肿瘤中浓聚程度较低；在其他起源于前肠的肿瘤（支气管）中则无明显浓聚。我们得出结论，131I是一种用于类癌肿瘤的有用显像剂。
