Synthesis and search for anticonvulsive and hypoglycemic properties of novel 5-benzylidene derivatives of 3-o-chloro- and 3-o-methylbenzoyl-2-thiohydantoin.

14 new benzylidene derivatives of 3-o-chloro- and 3-o-methylbenzoyl-2 thio hydantoin were synthesized. Their chemical structure was confirmed by IR, NMR and mass spectroscopy. Compounds 1-14 were tested for their anticonvulsant and hypoglycemic activity. Their toxicity was low and they showed only weak activity in tests for anticonvulsive and hypoglycemic properties.