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A search for new anticonvulsant compounds among 3-aryl-5-benzylidene derivatives of 2-thiohydantoin.

作者信息

Korohoda M J, Kleinrok Z, Przegaliński E

出版信息

Pol J Pharmacol Pharm. 1976 May-Jun;28(4):329-33.

PMID:981022
Abstract

13 New 3-aryl-5-benzylidene-2-thiohydantoins were obtained by condensation of 3-o-tolyl- and 3-m-tołyl-2--thiohydantoin with aromatic aldehydes. The structure of the obtained compounds was confirmed by IR spectra. Derivatives of 2-thiohydantoin 1-13 show weak anticonvulsant activity in pentetrazole test and show no protecting activity against the maximal electric shock.

摘要

相似文献

1
A search for new anticonvulsant compounds among 3-aryl-5-benzylidene derivatives of 2-thiohydantoin.
Pol J Pharmacol Pharm. 1976 May-Jun;28(4):329-33.
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[Search for anticonvulsants among 3-aryl-5-benzylidene and 3-aryl-5-naphtalyl derivatives of 2-thiohydantoin].
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[Synthesis and testing of anticonvulsant properties of 5-benzylidene derivatives of 3-o-, 3-m- I 3-p-chlorophenyl-2-thiohydantoin].
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