Guangzhou University of Chinese Medicine, Guangzhou, China.
First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou , China.
BMC Pediatr. 2021 Aug 12;21(1):339. doi: 10.1186/s12887-021-02755-4.
Perthes disease (Legg-Calvé-Perthes, LCP) is a self-limited and non-systemic disease occurring in the femoral heads of children, which is mainly manifested as an ischemic necrosis of the femoral head epiphysis, leading to subchondral ossification injury of the femoral head.
Here we report a case of 11-year-old child with long-term use of high-dose glucocorticoids. With MRI examination finding the epiphyseal necrosis of right humeral head, femur and tibia, and X-ray examination finding bilateral femoral head necrosis, the child was diagnosed as Perthes disease based on his clinical and imaging data.
Long-term and high-dose glucocorticoids may be one of the causes of Perthes disease.
佩特兹病（Legg-Calvé-Perthes，LCP）是一种发生在儿童股骨头的自限性和非系统性疾病，主要表现为股骨头骨骺缺血性坏死，导致股骨头软骨下骨化损伤。
我们在此报告一例 11 岁儿童，长期大剂量使用糖皮质激素。MRI 检查发现右侧肱骨头、股骨和胫骨骨骺坏死，X 线检查发现双侧股骨头坏死，根据患儿的临床和影像学资料，诊断为佩特兹病。
长期和大剂量糖皮质激素可能是佩特兹病的原因之一。
