St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090, Milan, Italy.
BMC Health Serv Res. 2021 Aug 12;21(1):801. doi: 10.1186/s12913-021-06828-z.
Selective lamellar corneal transplantation (keratoplasty) has overtaken full thickness penetrating keratoplasty as the graft choice for endothelial failure. Even more recently eye bank prepared tissues are becoming increasing popular as a way to reduce the risks of tissue loss and stress during endothelial keratoplasty preparation in the surgical theatre. This study compares costs between surgeon and eye bank prepared tissues for Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's membrane endothelial keratoplasty (DMEK).
Retrospective study conducted at the Royal Liverpool University Hospital including endothelial keratoplasties with a minimum of 6 months follow-up time. Cost analysis included surgical expenses, tissue acquisition fees, cost of patient's ward admission and out-patient expenses, including cost of re-bubbling procedures, costs of visits, anterior segment imaging and optometrist visits within the first 6 months follow-up.
Ninety-eight eyes of 98 patients were included in the study of which 42 underwent DSAEK surgery and 56 DMEK surgery. Cost analysis of surgical expenses in the DSAEK group showed a significant difference between using surgeon prepared and eye bank prepared tissue (£3866 ± 296 and £4389 ± 360, respectively; p < 0.01) and the same was found in the DMEK group (£3682 ± 167 and £4162 ± 167 for surgeon prepared and eye bank prepared tissues, respectively; p < 0.01). Cost of out-patient visits did not differ significantly in either group.
At the Royal Liverpool University Hospital, eye bank prepared tissues had higher surgical expenses compared to those prepared by the surgeon, while the post-operative care expenses were similar between the two groups.
选择性板层角膜移植术(角膜移植术)已取代全层穿透性角膜移植术,成为内皮功能衰竭的首选移植物。最近,眼库制备的组织越来越受欢迎,因为这种方法可以降低手术室内内皮角膜移植准备过程中组织丢失和应激的风险。本研究比较了用于 Descemet 剥离自动内皮角膜移植术(DSAEK)和 Descemet 膜内皮角膜移植术(DMEK)的外科医生和眼库制备组织之间的成本。
在利物浦皇家大学医院进行的回顾性研究,包括至少 6 个月随访时间的内皮角膜移植术。成本分析包括手术费用、组织获取费用、患者病房入院和门诊费用,包括重新鼓泡程序的费用、就诊费用、前节成像和眼科医生在随访的前 6 个月内的就诊费用。
本研究共纳入 98 例 98 只眼,其中 42 例接受 DSAEK 手术,56 例接受 DMEK 手术。DSAEK 组手术费用的成本分析显示,使用外科医生准备和眼库准备的组织之间存在显著差异(分别为 £3866±296 和 £4389±360;p<0.01),在 DMEK 组中也发现了同样的情况(分别为 £3682±167 和 £4162±167,用于外科医生准备和眼库准备的组织;p<0.01)。两组门诊就诊费用无显著差异。
在利物浦皇家大学医院,与外科医生准备的组织相比,眼库准备的组织具有更高的手术费用,而两组的术后护理费用相似。