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镓-68 DOTATATE正电子发射断层扫描/计算机断层扫描在嗅神经母细胞瘤罕见病例中的应用

Ga-68 DOTATATE Positron Emission Tomography/Computed Tomography in a Rare Case of Esthesioneuroblastoma.

作者信息

Verma Priyanka, Singh Braj Kishore, Singh Inderdeep, Soni Brijesh Kumar, Asopa Ramesh V

机构信息

Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.

Nuclear Medicine, INHS Asvini, Mumbai, Maharashtra, India.

出版信息

Indian J Nucl Med. 2021 Apr-Jun;36(2):217-219. doi: 10.4103/ijnm.ijnm_207_20. Epub 2021 Jun 21.

DOI:10.4103/ijnm.ijnm_207_20
PMID:34385802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8320821/
Abstract

We describe the Ga-68 DOTATATE positron emission tomography/computed tomography (PET/CT) findings of a 51-year-old man, operated for right esthesioneuroblastoma. Postoperative Ga-68 DOTATATE PET/CT revealed focal uptake anterior to sphenoid ostium on the right paramedian side, suspicious for residual disease. Magnetic resonance imaging showed an enhancing lesion in posterosuperior nasal cavity on the right side extending into the right sphenoid sinus. He underwent re-surgery and adjuvant chemoradiotherapy. The histopathology revealed residual olfactory neuroblastoma. The follow-up Ga-68 DOTATATE PET/CT was negative. This case emphasizes the role of Ga-68 DOTATATE PET/CT in the management, especially in residual or recurrent disease and potential radiotheranostics for these rare tumors.

摘要

我们描述了一名51岁因右侧嗅神经母细胞瘤接受手术的男性患者的镓-68 DOTATATE正电子发射断层扫描/计算机断层扫描（PET/CT）检查结果。术后镓-68 DOTATATE PET/CT显示右侧旁正中蝶窦口前方有局灶性摄取，怀疑有残留病灶。磁共振成像显示右侧鼻腔后上壁有强化病变，延伸至右侧蝶窦。他接受了再次手术和辅助放化疗。组织病理学显示为残留的嗅神经母细胞瘤。随访的镓-68 DOTATATE PET/CT结果为阴性。该病例强调了镓-68 DOTATATE PET/CT在治疗管理中的作用，尤其是在残留或复发性疾病方面，以及对这些罕见肿瘤潜在的放射核素治疗作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/8320821/9cc64adc3ef7/IJNM-36-217-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/8320821/99e2fa1b90da/IJNM-36-217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/8320821/9cc64adc3ef7/IJNM-36-217-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/8320821/99e2fa1b90da/IJNM-36-217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/8320821/9cc64adc3ef7/IJNM-36-217-g002.jpg

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本文引用的文献

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Esthesioneuroblastoma on 68Ga DOTANOC PET/CT.嗅神经母细胞瘤 68Ga-DOTANOC PET/CT 表现。
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Frequent expression of somatostatin receptor 2a in olfactory neuroblastomas: a new and distinctive feature.
嗅神经母细胞瘤中生长抑素受体 2a 的频繁表达：一个新的、独特的特征。
Hum Pathol. 2018 Sep;79:144-150. doi: 10.1016/j.humpath.2018.05.013. Epub 2018 May 25.
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Lutetium 177-DOTA-TATE therapy for esthesioneuroblastoma: A case report.镥-177-DOTA-奥曲肽治疗嗅神经母细胞瘤：一例报告。
Exp Ther Med. 2016 Nov;12(5):3078-3082. doi: 10.3892/etm.2016.3732. Epub 2016 Sep 20.
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