碳纳米管：一类日益流行的纳米材料的有益和危险方面综述
Carbon Nanotubes: A Summary of Beneficial and Dangerous Aspects of an Increasingly Popular Group of Nanomaterials.
作者信息
Zhang Chengke, Wu Licun, de Perrot Marc, Zhao Xiaogang
机构信息
Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Key Laboratory of Thoracic Cancer, Cheeloo College of Medicine, Shandong University, Jinan, China.
出版信息
Front Oncol. 2021 Jul 27;11:693814. doi: 10.3389/fonc.2021.693814. eCollection 2021.
Carbon nanotubes (CNTs) are nanomaterials with broad applications that are produced on a large scale. Animal experiments have shown that exposure to CNTs, especially one type of multi-walled carbon nanotube, MWCNT-7, can lead to malignant transformation. CNTs have characteristics similar to asbestos (size, shape, and biopersistence) and use the same molecular mechanisms and signaling pathways as those involved in asbestos tumorigenesis. Here, a comprehensive review of the characteristics of carbon nanotubes is provided, as well as insights that may assist in the design and production of safer nanomaterials to limit the hazards of currently used CNTs.
碳纳米管（CNTs）是具有广泛应用且大规模生产的纳米材料。动物实验表明，接触碳纳米管，尤其是一种多壁碳纳米管MWCNT - 7，可导致恶性转化。碳纳米管具有与石棉相似的特性（尺寸、形状和生物持久性），并使用与石棉肿瘤发生相关的相同分子机制和信号通路。在此，提供了对碳纳米管特性的全面综述，以及有助于设计和生产更安全纳米材料以限制当前使用的碳纳米管危害的见解。
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