van Oirschot Janneke, Ooms Gaby I, Waldmann Benjamin, Kadam Priyanka
Health Action International, Amsterdam, the Netherlands.
Utrecht Centre for Pharmaceutical Policy and Regulation, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands.
Toxicon X. 2021 Jul 15;9-10:100075. doi: 10.1016/j.toxcx.2021.100075. eCollection 2021 Jul.
Snakebite envenoming is a long-neglected disease causing significant morbidity and mortality in snakebite endemic low- and middle-income countries (LMICs). Global awareness on snakebite was increasing steadily up to 2020, and an increasing number of countries began to acknowledge the issue, when coronavirus disease 2019 (COVID-19) started to have an unprecedented impact on societies and health systems. To better understand how snakebite incidents, prevention and care are being affected during this global emergency, we collected perspectives of snakebite community- and health system stakeholders in a qualitative key-informant study. An open-ended survey and semi-structured interviews were conducted to gather information on changes in snakebite occurrence and circumstances, community responses, access to care and health outcomes in LMICs since the COVID-19 pandemic. Forty-three informants from 21 countries participated in the study. Based on informants' experiences, in spite of COVID-19 lockdowns, exposure to snakes did not change in many rural agrarian communities, where incidences are usually highest. However, we did find several access to care issues relating to avoidance of formal care, transport barriers, overburdened healthcare systems and -providers, and antivenom manufacturing and supply disruptions, which were unique per context. On a brighter note, ventilator availability had increased in several countries, although not automatically benefitting snakebite patients directly. In conclusion, we found apparent effects of the COVID-19 pandemic on snakebite prevention and care, although its severity was highly context- and time-dependent. Interactions between the pandemic effects and snakebite incidents most severely impact remote rural communities, showing the need to invest in community-based prevention and care.
蛇咬伤中毒是一种长期被忽视的疾病,在蛇咬伤流行的低收入和中等收入国家(LMICs)造成了严重的发病率和死亡率。直到2020年,全球对蛇咬伤的认识一直在稳步提高,越来越多的国家开始认识到这个问题,当时2019冠状病毒病(COVID-19)开始对社会和卫生系统产生前所未有的影响。为了更好地了解在这场全球紧急情况中蛇咬伤事件、预防和护理是如何受到影响的,我们在一项定性关键信息提供者研究中收集了蛇咬伤社区和卫生系统利益相关者的观点。开展了一项开放式调查和半结构化访谈,以收集自COVID-19大流行以来低收入和中等收入国家蛇咬伤发生率和情况的变化、社区反应、获得护理的情况以及健康结果等方面的信息。来自21个国家的43名信息提供者参与了这项研究。根据信息提供者的经验,尽管实施了COVID-19封锁措施,但在许多农村农业社区,人们接触蛇的情况并没有改变,而这些社区的蛇咬伤发生率通常是最高的。然而,我们确实发现了几个与避免接受正规护理、交通障碍、医疗系统和提供者负担过重以及抗蛇毒血清生产和供应中断有关的获得护理问题,这些问题因具体情况而异。值得庆幸的是,一些国家的呼吸机可用性有所增加,尽管这并没有直接使蛇咬伤患者受益。总之,我们发现COVID-19大流行对蛇咬伤预防和护理产生了明显影响,但其严重程度高度依赖于具体情况和时间。大流行影响与蛇咬伤事件之间的相互作用对偏远农村社区的影响最为严重,这表明需要投资于基于社区的预防和护理。