Matsukawa Keitaro, Yanai Yoshihide, Fujiyoshi Kanehiro, Kato Takashi, Yato Yoshiyuki
J Neurosurg Spine. 2021 Aug 13;35(5):601-606. doi: 10.3171/2021.2.SPINE202229. Print 2021 Nov 1.
Contrary to original cortical bone trajectory (CBT), "long CBT" directed more anteriorly in the vertebral body has recently been recommended because of improved screw fixation and load sharing within the vertebra. However, to the authors' knowledge there has been no report on the clinical significance of the screw length and screw insertion depth used with the long CBT technique. The aim of the present study was to investigate the influence of the screw insertion depth in the vertebra on lumbar spinal fusion using the CBT technique.
A total of 101 consecutive patients with L4 degenerative spondylolisthesis who underwent single-level posterior lumbar interbody fusion at L4-5 using the CBT technique were included (mean follow-up 32.9 months). Screw loosening and bone fusion were radiologically assessed to clarify the factors contributing to these outcomes. Investigated factors were as follows: 1) age, 2) sex, 3) body mass index, 4) bone mineral density, 5) intervertebral mobility, 6) screw diameter, 7) screw length, 8) depth of the screw in the vertebral body (%depth), 9) facetectomy, 10) crosslink connector, and 11) cage material.
The incidence of screw loosening was 3.1% and bone fusion was achieved in 91.7% of patients. There was no significant factor affecting screw loosening. The %depth in the group with bone fusion [fusion (+)] was significantly higher than that in the group without bone fusion [fusion (-)] (50.3% ± 8.2% vs 37.0% ± 9.5%, respectively; p = 0.001), and multivariate logistic regression analysis revealed that %depth was a significant independent predictor of bone fusion. Receiver operating characteristic curve analysis identified %depth > 39.2% as a predictor of bone fusion (sensitivity 90.9%, specificity 75.0%).
This study is, to the authors' knowledge, the first to investigate the significance of the screw insertion depth using the CBT technique. The cutoff value of the screw insertion depth in the vertebral body for achieving bone fusion was 39.2%.
与原始皮质骨轨迹(CBT)相反,由于椎体内部螺钉固定和负荷分担得到改善,近来有人推荐“长CBT”,其在椎体中更向前。然而,据作者所知,尚无关于长CBT技术中螺钉长度和螺钉置入深度的临床意义的报告。本研究的目的是探讨椎体中螺钉置入深度对采用CBT技术的腰椎融合的影响。
纳入101例连续的L4退行性椎体滑脱患者,这些患者在L4-5节段采用CBT技术接受了单节段后路腰椎椎间融合术(平均随访32.9个月)。通过影像学评估螺钉松动和骨融合情况,以明确导致这些结果的因素。研究的因素如下:1)年龄,2)性别,3)体重指数,4)骨密度,5)椎间活动度,6)螺钉直径,7)螺钉长度,8)螺钉在椎体中的深度(深度百分比),9)小关节切除术,10)横向连接装置,以及11)椎间融合器材料。
螺钉松动发生率为3.1%,91.7%的患者实现了骨融合。没有影响螺钉松动的显著因素。骨融合组[融合(+)]的深度百分比显著高于未融合组[融合(-)](分别为50.3%±8.2%和37.0%±9.5%;p = 0.001),多因素逻辑回归分析显示深度百分比是骨融合的显著独立预测因素。受试者工作特征曲线分析确定深度百分比>39.2%为骨融合的预测指标(敏感性90.9%,特异性75.0%)。
据作者所知,本研究首次探讨了采用CBT技术时螺钉置入深度的意义。实现骨融合的椎体中螺钉置入深度的临界值为39.2%。