正电子发射断层扫描中的新型示踪剂和放射性核素
Novel Tracers and Radionuclides in PET Imaging.
机构信息
Department of Radiology, Memorial Sloan Kettering Cancer Center, 417 East 68th Street, New York, NY 10065, USA.
School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
出版信息
Radiol Clin North Am. 2021 Sep;59(5):887-918. doi: 10.1016/j.rcl.2021.05.012.
The use of PET imaging agents in oncology, cardiovascular disease, and neurodegenerative disease shows the power of this technique in evaluating the molecular and biological characteristics of numerous diseases. These agents provide crucial information for designing therapeutic strategies for individual patients. Novel PET tracers are in continual development and many have potential use in clinical and research settings. This article discusses the potential applications of tracers in diagnostics, the biological characteristics of diseases, the ability to provide prognostic indicators, and using this information to guide treatment strategies including monitoring treatment efficacy in real time to improve outcomes and survival.
正电子发射断层扫描（PET）成像剂在肿瘤学、心血管疾病和神经退行性疾病中的应用，展示了这项技术在评估众多疾病的分子和生物学特征方面的强大功能。这些试剂为设计个体化患者的治疗策略提供了关键信息。新型的 PET 示踪剂正在不断开发中，许多示踪剂在临床和研究环境中具有潜在用途。本文讨论了示踪剂在诊断、疾病的生物学特征、提供预后指标的能力方面的潜在应用，以及如何利用这些信息来指导治疗策略，包括实时监测治疗效果以改善预后和生存率。
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