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尼日利亚阿布贾高血压患者血脂异常模式。

Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria.

机构信息

Department of Internal Medicine, College of Medicine and Health Sciences, Nile University of Nigeria, Asokoro District Hospital, Abuja, Nigeria.

Department of Surgery, College of Medicine and Health Sciences, Nile University of Nigeria, Asokoro District Hospital, Abuja, Nigeria.

出版信息

Pan Afr Med J. 2021 May 4;39:11. doi: 10.11604/pamj.2021.39.11.28807. eCollection 2021.

Abstract

INTRODUCTION

dyslipidemia and hypertension are independent cardiovascular risk factors that are linked by insulin resistance and commonly coexist as components of the metabolic syndrome. The consequences of dyslipidaemic patterns includes high cardiovascular risk profile and sequalae. Data on lipid patterns amongst hypertensive patients in Abuja, a city with affluent pattern of life style and rising cardiovascular risk profile is very scanty or limited to just levels of total plasma cholesterol. This study was aimed at determining the pattern and frequencies of dyslipidaemic forms among hypertensive patients in Abuja.

METHODS

this was a retrospective cohort study with the following data collected; socio-demographics, anthropometric measures and certain metabolic parameters from the new and old groups and analyzed using IBM SPSS Statistics, version 23. All decisions were made using the assymp. Two-sided Pearson χ2 probability. Quantitative variables were expressed as means and standard deviations. Qualitative variables were expressed as percentages. A p-value of ≤0.05 was set as significant.

RESULTS

eight hundred and fifty eight (858) cases were enrolled for this study, 704 (82.1%) olds and 154 (17.9%) news. There were 251 (29.3%) males and 607 (70.7%) females. The means of the two groups were largely comparable. The commonest dyslipidaemic type was reduced High density lipoprotein, HDL (96.1%), followed by elevated low-density lipoprotein, LDL (78.6%), then, elevated total cholesterol, (62.3%) TCHOL and elevated triglycerides, TG 43.5%.

CONCLUSION

dyslipidemic forms are very common among hypertensive patients in Abuja, Nigeria, particularly reduced HDL. Some observed associations include; middle age, female gender, middle/upper socio-economic classes, low levels of physical activity, overweight/obesity, dysglycaemia and long-standing hypertension.

摘要

简介

血脂异常和高血压是独立的心血管危险因素,它们通过胰岛素抵抗相互关联,通常共同存在于代谢综合征中。血脂异常模式的后果包括心血管风险高和后遗症。关于阿布贾高血压患者血脂模式的数据非常稀缺或仅限于总血浆胆固醇水平。本研究旨在确定阿布贾高血压患者血脂异常形式的模式和频率。

方法

这是一项回顾性队列研究,收集了新老两组患者的社会人口统计学、人体测量学指标和某些代谢参数,并使用 IBM SPSS Statistics 版本 23 进行分析。所有决策均使用 assymp。双尾 Pearson χ2 概率。定量变量表示为平均值和标准差。定性变量表示为百分比。p 值≤0.05 为显著。

结果

本研究共纳入 858 例患者,704 例为老年组(82.1%),154 例为新病例组(17.9%)。男性 251 例(29.3%),女性 607 例(70.7%)。两组的平均值基本相当。最常见的血脂异常类型是高密度脂蛋白(HDL)降低(96.1%),其次是低密度脂蛋白(LDL)升高(78.6%),然后是总胆固醇(TCHOL)升高(62.3%)和甘油三酯(TG)升高(43.5%)。

结论

尼日利亚阿布贾的高血压患者血脂异常形式非常常见,特别是 HDL 降低。一些观察到的关联包括:中年、女性、中/上层社会经济阶层、低体力活动水平、超重/肥胖、血糖异常和长期高血压。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2c/8348252/7d6b930dc5f6/PAMJ-39-11-g001.jpg

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