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COVID-19 暴露出脑内钙化。

COVID-19 Unveiling Brain Calcifications.

机构信息

Laboratório de Imunopatologia Keizo Asami, Federal University of Pernambuco, Recife, Pernambuco, 50670-901, Brazil.

出版信息

J Mol Neurosci. 2022 Jan;72(1):25-26. doi: 10.1007/s12031-021-01899-3. Epub 2021 Aug 15.

DOI:10.1007/s12031-021-01899-3
PMID:34396455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8364776/
Abstract

Neurological symptoms in COVID-19 patients have attracted the interest of the scientific community, yet their mechanisms remain unknown. In some circumstances, the presence of neurological manifestations may result in an incidental diagnosis after a detailed investigation. In the present letter, we discuss a case published by Demir et al., in which the diagnosis of COVID-19 enabled the diagnosis of a rare neurological disorder, characterized by bilateral brain calcifications, commonly known by the eponym Fahr's syndrome. In addition, we report a case of primary brain calcifications unveiled by a suspected coronavirus infection.

摘要

COVID-19 患者的神经系统症状引起了科学界的关注,但这些症状的发生机制仍不清楚。在某些情况下,详细检查后可能会发现神经系统表现,从而偶然诊断出某种疾病。在本函中,我们讨论了 Demir 等人发表的一个病例,该病例中 COVID-19 的诊断促成了一种罕见的神经疾病的诊断,这种疾病的特征是双侧大脑钙化,通常以 Fahr 综合征的别名命名。此外,我们报告了一例疑似冠状病毒感染引发的原发性脑钙化病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/8364776/15f554a296aa/12031_2021_1899_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/8364776/c8c3451dee68/12031_2021_1899_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/8364776/15f554a296aa/12031_2021_1899_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/8364776/c8c3451dee68/12031_2021_1899_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/8364776/15f554a296aa/12031_2021_1899_Fig2_HTML.jpg

相似文献

1
COVID-19 Unveiling Brain Calcifications.COVID-19 暴露出脑内钙化。
J Mol Neurosci. 2022 Jan;72(1):25-26. doi: 10.1007/s12031-021-01899-3. Epub 2021 Aug 15.
2
Fahr's syndrome presenting with seizures in SARS-CoV-2 (COVID-19) pneumonia-a case report.Fahr 综合征在 SARS-CoV-2(COVID-19)肺炎中伴发癫痫发作:一例报告。
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Fahr's disease: an incidental finding in a patient of tubercular meningitis.法尔病:结核性脑膜炎患者的偶然发现。
BMJ Case Rep. 2012 Dec 3;2012:bcr2012007136. doi: 10.1136/bcr-2012-007136.
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Fahr's syndrome.法尔综合征。
Intern Emerg Med. 2019 Apr;14(3):483-484. doi: 10.1007/s11739-018-1998-4. Epub 2018 Nov 30.
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Fahr's Syndrome Associated with Multiple Intracranial Aneurysms: A Case Report.法尔综合征合并多发颅内动脉瘤:一例报告
Turk Neurosurg. 2016;26(4):643-5. doi: 10.5137/1019-5149.JTN.8574-13.0.
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Fahr's disease presenting with dementia at onset: a case report and literature review.首发痴呆的 Fahr 病:病例报告及文献复习。
Behav Neurol. 2014;2014:750975. doi: 10.1155/2014/750975. Epub 2014 Mar 12.
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Psychosis revealing familial idiopathic basal ganglia calcification.精神病学揭示家族性特发性基底节钙化。
Gen Hosp Psychiatry. 2013 Sep-Oct;35(5):575.e3-5. doi: 10.1016/j.genhosppsych.2012.09.008. Epub 2012 Oct 31.
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Sepsis Unmasking Fahr's Disease.脓毒症揭示了 Fahr 病。
Am J Med Sci. 2020 Oct;360(4):406-409. doi: 10.1016/j.amjms.2020.05.023. Epub 2020 May 21.
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Corticobasal degeneration syndrome with basal ganglia calcification: Fahr's disease as a corticobasal look-alike?伴有基底节钙化的皮质基底节变性综合征:法尔病会是类似皮质基底节变性的疾病吗?
Mov Disord. 2002 May;17(3):563-7. doi: 10.1002/mds.10122.
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CT findings in Fahr's disease.法尔病的CT表现。
BMJ Case Rep. 2015 Mar 20;2015:bcr2014208812. doi: 10.1136/bcr-2014-208812.

引用本文的文献

1
Routine Brain MRI Findings on the Long-Term Effects of COVID-19: A Scoping Review.新冠病毒病长期影响的常规脑部磁共振成像结果:一项范围综述
Diagnostics (Basel). 2023 Jul 30;13(15):2533. doi: 10.3390/diagnostics13152533.
2
Incidental diagnosis of Fahr's syndrome after coronavirus disease 2019 infection with the fatal outcome.2019冠状病毒病感染后偶然诊断出法尔综合征并导致致命后果。
Hippokratia. 2022 Oct-Dec;26(4):161.

本文引用的文献

1
The Need for Consensus on Primary Familial Brain Calcification Nomenclature.原发性家族性脑钙化命名达成共识的必要性。
J Neuropsychiatry Clin Neurosci. 2018 Fall;30(4):291-293. doi: 10.1176/appi.neuropsych.18030044. Epub 2018 Jul 26.