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法尔病:结核性脑膜炎患者的偶然发现。

Fahr's disease: an incidental finding in a patient of tubercular meningitis.

作者信息

Aggarwal Puneet, Kumar Gunjan, Dev Nishanth, Jain Shalabh

机构信息

Department Internal Medicine, PGIMER & Dr. Ram Manohar Lohia Hospital, New Delhi, India.

出版信息

BMJ Case Rep. 2012 Dec 3;2012:bcr2012007136. doi: 10.1136/bcr-2012-007136.

Abstract

Fahr's disease, also known as idiopathic basal ganglia calcification, is a rare clinical entity characterised by bilaterally symmetric calcification of the basal ganglia. Most of the patients present with extrapyramidal symptoms, but the natural history, progression and treatment still remain unknown. We report a case of tubercular meningitis diagnosed by a cerebrospinal fluid examination with incidental findings of an extensive basal ganglia calcification on CT. CT of sibling, done to evaluate an episode of seizure, revealed strikingly similar calcification. Both these calcifications were due to Fahr's disease. The patient was treated with antitubercular and antiepileptic drugs. The patient fully recovered clinically and currently is seizure-free on antiepileptic treatment.

摘要

法尔病,也称为特发性基底节钙化,是一种罕见的临床病症,其特征为基底节双侧对称性钙化。大多数患者表现为锥体外系症状,但其自然病史、病情进展及治疗方法仍不明确。我们报告一例经脑脊液检查诊断为结核性脑膜炎的病例,CT检查偶然发现广泛的基底节钙化。为评估一次癫痫发作而对其同胞进行的CT检查显示出极为相似的钙化。这两处钙化均由法尔病所致。该患者接受了抗结核和抗癫痫药物治疗。患者临床完全康复,目前在接受抗癫痫治疗期间未再发作。

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本文引用的文献

2
An unusual case of Fahr's disease.
Arq Neuropsiquiatr. 2009 Jun;67(2B):516-8. doi: 10.1590/s0004-282x2009000300029.
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Familial Fahr disease in a Turkish family.一个土耳其家庭中的家族性法尔病。
South Med J. 2009 Jan;102(1):85-6. doi: 10.1097/SMJ.0b013e3181833f02.
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Tuberculous meningitis.结核性脑膜炎
Med Clin North Am. 1985 Mar;69(2):315-31. doi: 10.1016/s0025-7125(16)31045-8.

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