Duke-NUS Medical School, Singapore, Singapore.
Programme in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.
J Med Internet Res. 2021 Aug 13;23(8):e25002. doi: 10.2196/25002.
The management of diabetes is complex. There is growing recognition of the use of patient-reported outcome measures (PROMs) as a standardized method of obtaining an outlook on patients' functional status and well-being. However, no systematic reviews have summarized the studies that investigate the measurement properties of diabetes PROMs.
Our aims were to conduct a systematic review of studies investigating the measurement properties of diabetes PROMs by evaluating the methodological quality and overall level of evidence of these PROMs and to categorize them based on the outcome measures assessed.
This study was guided by the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. Relevant articles were retrieved from the Embase, PubMed, and PsychINFO databases. The PROMs were evaluated with the COSMIN (COnsensus-based Standards for the selection of health Measurement Instruments) guidelines.
A total of 363 articles evaluating the measurement properties of PROMs for diabetes in the adult population were identified, of which 238 unique PROMs from 248 studies reported in 209 articles were validated in the type 2 diabetes population. PROMs with at least a moderate level of evidence for ≥5 of 9 measurement properties include the Chinese version of the Personal Diabetes Questionnaire (C-PDQ), Diabetes Self-Management Instrument Short Form (DSMI-20), and Insulin Treatment Appraisal Scale in Hong Kong primary care patients (C-ITAS-HK), of which the C-PDQ has a "sufficient (+)" rating for >4 measurement properties. A total of 43 PROMs meet the COSMIN guidelines for recommendation for use.
This study identified and synthesized evidence for the measurement properties of 238 unique PROMs for patients with type 2 diabetes and categorized the PROMs according to their outcome measures. These findings may assist clinicians and researchers in selecting appropriate high-quality PROMs for clinical practice and research.
PROSPERO International Prospective Register of Systematic Reviews CRD42020180978; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020180978.
糖尿病的管理非常复杂。人们越来越认识到使用患者报告的结局测量（PROMs）作为获取患者功能状态和幸福感的标准化方法。然而，目前尚无系统评价总结调查糖尿病 PROMs 测量特性的研究。
本研究旨在通过评估这些 PROMs 的方法学质量和整体证据水平，对调查糖尿病 PROMs 测量特性的研究进行系统评价，并根据评估的结局测量对其进行分类。
本研究遵循 PRISMA（系统评价和荟萃分析的首选报告项目）指南。从 Embase、PubMed 和 PsychINFO 数据库中检索相关文章。使用 COSMIN（健康测量仪器选择的共识标准）指南评估 PROMs。
共确定了 363 篇评估成人糖尿病患者 PROMs 测量特性的文章，其中 248 项研究报告了 238 种独特的 PROMs，这些 PROMs在 209 篇文章中在 2 型糖尿病患者中得到验证。至少有 5 项/9 项测量特性具有中度证据水平的 PROM 包括中文版个人糖尿病问卷（C-PDQ）、糖尿病自我管理工具简短版（DSMI-20）和香港基层医疗患者胰岛素治疗评估量表（C-ITAS-HK），其中 C-PDQ 在>4 项测量特性上具有“充分（+）”评级。共有 43 种 PROM 符合 COSMIN 使用建议指南。
本研究确定并综合了 238 种用于 2 型糖尿病患者的独特 PROMs 的测量特性，并根据其结局测量对 PROM 进行了分类。这些发现可能有助于临床医生和研究人员在临床实践和研究中选择合适的高质量 PROM。
PROSPERO 国际前瞻性系统评价注册库 CRD42020180978；https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020180978。
