Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey.
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Lokman Hekim University, Ankara, Turkey.
J Back Musculoskelet Rehabil. 2022;35(3):633-639. doi: 10.3233/BMR-210032.
Piriformis syndrome (PS) is the common entrapment neuropathy causing buttock pain. Patients are conventionally treated with lifestyle modification, exercise, non-steroidal anti-inflammatory drugs, corticosteroid or botulinum toxin injections. However, some patients may not respond to these conventional treatment methods. Platelet rich plasma (PRP) injection has been shown to be beneficial in various muscular injuries, but its effects have not yet been investigated in PS.
The aim of this study was to explore the effect of PRP on pain and functional status in patients with PS, and to identify any correlations between clinical changes and demographic features.
A total of 60 patients with PS were randomly separated into two groups (PRP and control groups). All patients received one session of either PRP or saline injection performed under ultrasound guidance. The pain was measured with a visual analog scale (VAS) and Oswestry Disability Index (ODI) scores were noted at three intervals in both groups: before treatment, 1 week after treatment and 1 month after treatment.
The VAS and ODI scores were improved in both groups. The improvement was more obvious in the PRP group in the first week, and the results were similar for both groups when measured 1 month after the treatment.
Ultrasound-guided PRP injection provided greater improvements in both pain and functional status in patients with PS, starting in the early period after treatment. A repeat injection might be needed for a long-term effect.
梨状肌综合征（PS）是一种常见的卡压性周围神经病，可导致臀部疼痛。患者通常采用生活方式改变、运动、非甾体抗炎药、皮质类固醇或肉毒毒素注射等方法进行治疗。然而，有些患者可能对这些常规治疗方法无反应。富血小板血浆（PRP）注射已被证明对各种肌肉损伤有益，但尚未对 PS 进行研究。
本研究旨在探讨 PRP 对 PS 患者疼痛和功能状态的影响，并确定临床变化与人口统计学特征之间的任何相关性。
将 60 例 PS 患者随机分为两组（PRP 组和对照组）。所有患者均接受一次超声引导下 PRP 或生理盐水注射。采用视觉模拟评分（VAS）测量疼痛，在两组中分别于三个时间点（治疗前、治疗后 1 周和治疗后 1 个月）记录 Oswestry 残疾指数（ODI）评分。
两组的 VAS 和 ODI 评分均得到改善。PRP 组在治疗后第 1 周改善更为明显，治疗后 1 个月时两组结果相似。
超声引导下 PRP 注射可在治疗早期显著改善 PS 患者的疼痛和功能状态。可能需要重复注射以获得长期效果。
