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宫颈癌放疗后骶骨不全骨折的诊断:三例报告

Diagnosing sacral insufficiency fractures after radiotherapy in women with cervical cancer: Report of three cases.

作者信息

Sabaliauskas Vykintas, Tiškevičius Sigitas

机构信息

Department of Nuclear Medicine, National Cancer Institute, Vilnius, Lithuania.

出版信息

Radiol Case Rep. 2021 Aug 3;16(10):2938-2944. doi: 10.1016/j.radcr.2021.07.017. eCollection 2021 Oct.

Abstract

INTRODUCTION

Diagnosing sacral insufficiency fractures (SIF) in oncology patients is a challenge to radiologists, and recognition of imaging features is essential in order to avoid misdiagnosis of bone metastases and prevent patients from inaccurate treatment.

CLINICAL CASES

in order to better understand the essence of this pathology and to make diagnosis easier, we present three clinical cases of SIF in patients with cervical cancer. All patients received radiation therapy (external beam radiation and brachytherapy) and chemotherapy with cisplatin. Patients underwent pelvic MRI, CT, SPECT or SPECT/CT examinations. One patient underwent a FDG-PET/CT examination.

CONCLUSIONS

SPECT/CT should be included in the differential diagnostics when radiological features of pelvic bone pathology on CT or MRI are undetermined or SIF are suspected. SIF must always be considered in oncology patients with pelvic pain, especially in postmenopausal state and after radiation therapy. For patients with osteoporosis, bone density screening and precise review of the most common fracture sites are recommended.

摘要

引言

诊断肿瘤患者的骶骨不全骨折(SIF)对放射科医生来说是一项挑战,识别影像学特征对于避免骨转移的误诊以及防止患者接受不准确的治疗至关重要。

临床病例

为了更好地理解这种病理的本质并使诊断更容易,我们展示了三例宫颈癌患者的SIF临床病例。所有患者均接受了放射治疗(外照射放疗和近距离放疗)以及顺铂化疗。患者接受了盆腔MRI、CT、SPECT或SPECT/CT检查。一名患者接受了FDG-PET/CT检查。

结论

当CT或MRI上盆腔骨病变的放射学特征不明确或怀疑为SIF时,SPECT/CT应纳入鉴别诊断。对于有盆腔疼痛的肿瘤患者,尤其是绝经后状态和放疗后的患者,必须始终考虑SIF。对于骨质疏松患者,建议进行骨密度筛查并精确检查最常见的骨折部位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecb9/8350190/c4b74ea0502b/gr1.jpg

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