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嫌色性肾细胞癌:一例病例报告及文献综述

Chromophobe renal cell carcinoma: A case report and literature review.

作者信息

Ballati Ahmed, Essaidi Zakaria, El Jai Saad Rifki, Hajri Amal, Errguibi Driss, Boufettal Rachid, Chehab Farid

机构信息

Departement of General Surgery, University Hospital Centre Ibn Rochd, Faculty of Medecine and Pharmacy, Hassan II University, 9,Gascogne Street, Casablanca, Morocco.

出版信息

Ann Med Surg (Lond). 2021 Jul 28;68:102643. doi: 10.1016/j.amsu.2021.102643. eCollection 2021 Aug.

DOI:10.1016/j.amsu.2021.102643
PMID:34401129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8350170/
Abstract

INTRODUCTION

Chromophobe renal cell carcinoma, a distinct subtype of renal cell carcinoma (RCC) with characteristic light microscopic, histochemical, and ultrastructural features, typically has a favorable clinical course.

PRESENTATION OF CASE

A 45-year-old femele presented with abdominal pain. A physical examination found a palpable mass in the left upper quadrant of the abdomen. A CT scan of the abdomen showed a heterogeneously enhancing mass, with necrosis and calcifications contents betwen the liver and the right kidney. she underwent surgical resection. Partial nephrectomy was performed. Pathological diagnosis was Chromophobe renal cell carcinoma.

DISCUSSION AND CONCLUSION

Chromophobe RCC is a rare variety of kidney neoplasm that has recently been better characterized from a molecular and genetic perspective. Overall, it is considered to have a better prognosis, and is associated with earlier stage tumors and longer overall survival compared with clear cell RCC.

摘要

引言

嫌色性肾细胞癌是肾细胞癌(RCC)的一种独特亚型,具有特征性的光镜、组织化学和超微结构特征,通常临床病程良好。

病例介绍

一名45岁女性因腹痛就诊。体格检查发现左上腹可触及肿块。腹部CT扫描显示一个不均匀强化的肿块,肝脏和右肾之间有坏死和钙化成分。她接受了手术切除,行部分肾切除术。病理诊断为嫌色性肾细胞癌。

讨论与结论

嫌色性肾细胞癌是一种罕见的肾脏肿瘤,最近从分子和遗传学角度得到了更好的描述。总体而言,它被认为预后较好,与透明细胞肾细胞癌相比,与早期肿瘤和更长的总生存期相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703d/8350170/e0442a0848a7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703d/8350170/d18fb2eadccf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703d/8350170/e0442a0848a7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703d/8350170/d18fb2eadccf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703d/8350170/e0442a0848a7/gr2.jpg

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本文引用的文献

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Open partial nephrectomy: current review.开放性部分肾切除术:当前综述
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Chromophobe renal cell carcinoma: current and controversial issues.嫌色细胞性肾细胞癌:当前和有争议的问题。
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The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
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Urol Oncol. 2020 Apr;38(4):137-149. doi: 10.1016/j.urolonc.2019.11.006. Epub 2020 Jan 15.
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Chromophobe renal cell carcinoma: a clinicopathologic study of 203 tumors in 200 patients with primary resection at a single institution.嫌色细胞肾细胞癌:单中心 200 例患者行初次切除术的 203 例肿瘤的临床病理研究。
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Chromophobe renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 145 cases.嫌色性肾细胞癌:145例的组织形态学特征及传统病理预后参数评估
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