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嫌色性肾细胞癌:一例病例报告及文献综述

Chromophobe renal cell carcinoma: A case report and literature review.

作者信息

Ballati Ahmed, Essaidi Zakaria, El Jai Saad Rifki, Hajri Amal, Errguibi Driss, Boufettal Rachid, Chehab Farid

机构信息

Departement of General Surgery, University Hospital Centre Ibn Rochd, Faculty of Medecine and Pharmacy, Hassan II University, 9,Gascogne Street, Casablanca, Morocco.

出版信息

Ann Med Surg (Lond). 2021 Jul 28;68:102643. doi: 10.1016/j.amsu.2021.102643. eCollection 2021 Aug.

Abstract

INTRODUCTION

Chromophobe renal cell carcinoma, a distinct subtype of renal cell carcinoma (RCC) with characteristic light microscopic, histochemical, and ultrastructural features, typically has a favorable clinical course.

PRESENTATION OF CASE

A 45-year-old femele presented with abdominal pain. A physical examination found a palpable mass in the left upper quadrant of the abdomen. A CT scan of the abdomen showed a heterogeneously enhancing mass, with necrosis and calcifications contents betwen the liver and the right kidney. she underwent surgical resection. Partial nephrectomy was performed. Pathological diagnosis was Chromophobe renal cell carcinoma.

DISCUSSION AND CONCLUSION

Chromophobe RCC is a rare variety of kidney neoplasm that has recently been better characterized from a molecular and genetic perspective. Overall, it is considered to have a better prognosis, and is associated with earlier stage tumors and longer overall survival compared with clear cell RCC.

摘要

引言

嫌色性肾细胞癌是肾细胞癌(RCC)的一种独特亚型,具有特征性的光镜、组织化学和超微结构特征,通常临床病程良好。

病例介绍

一名45岁女性因腹痛就诊。体格检查发现左上腹可触及肿块。腹部CT扫描显示一个不均匀强化的肿块,肝脏和右肾之间有坏死和钙化成分。她接受了手术切除,行部分肾切除术。病理诊断为嫌色性肾细胞癌。

讨论与结论

嫌色性肾细胞癌是一种罕见的肾脏肿瘤,最近从分子和遗传学角度得到了更好的描述。总体而言,它被认为预后较好,与透明细胞肾细胞癌相比,与早期肿瘤和更长的总生存期相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703d/8350170/d18fb2eadccf/gr1.jpg

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