Department of Pathology, Ibn Rochd University Hospital Center, Casablanca, Morocco.
Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Casablanca, Morocco.
Pan Afr Med J. 2022 Jul 14;42:206. doi: 10.11604/pamj.2022.42.206.34595. eCollection 2022.
Chromophobe renal cell carcinoma with liposarcomatous dedifferentiation is a very extremely rare tumor and only few cases have been reported in the literature. Here we report a case of a 37-year-old woman who presented with a pain and a palpable mass in the right flank. The abdominal computed tomography (CT) scan found a renal tumor and the patient underwent a right radical nephrectomy with adrenal gland resection. After the histological examination of the specimen completed by immunohistochemical and molecular study, a diagnosis of chromophobe renal cell carcinoma with liposarcomatous dedifferentiation was made. The patient received adjuvant chemotherapy. Afterwards, she developed bone metastasis and died 13 months after the surgery. Chromophobe renal cell carcinoma with liposarcomatous dedifferentiation is a rare tumor associated with a poor prognosis and a metastatic potential.
伴脂肪肉瘤去分化的嫌色细胞肾细胞癌是一种非常罕见的肿瘤，文献中仅报道了少数病例。在此，我们报告了 1 例 37 岁女性，因右侧腰部疼痛和可触及肿块就诊。腹部 CT 扫描发现肾肿瘤，患者接受了右肾癌根治性切除术和肾上腺切除术。免疫组织化学和分子研究完成标本的组织学检查后，诊断为伴脂肪肉瘤去分化的嫌色细胞肾细胞癌。患者接受了辅助化疗。随后，她发生了骨转移，术后 13 个月死亡。伴脂肪肉瘤去分化的嫌色细胞肾细胞癌是一种罕见的肿瘤，预后不良，具有转移潜能。
