Panitz Nydia, Gerhardt Kristin, Becker Cornelia, Schleife Hendrikje, Bach Enrica, Opitz Sabine, Schaudinn Alexander, Platzbecker Uwe, Kayser Sabine
Medical Clinic and Policlinic I Hematology and Cellular Therapy University Hospital Leipzig Leipzig Germany.
Medical practice for Hematology and Oncology Leipzig Germany.
Clin Case Rep. 2021 Aug 6;9(8):e04557. doi: 10.1002/ccr3.4557. eCollection 2021 Aug.
BALT lymphoma is a rare B-NHL with a favorable prognosis. We here report on two patients with nonspecific symptoms: one showed as major symptom severe thrombocytopenia and the other dyspnea and dry cough, thereby suggesting an inflammatory focus in the lungs. There is no standard of care established yet. Both patients were successfully treated with rituximab and bendamustine. Thus, combined immunochemotherapy should be considered as first-line therapy as in other MALT lymphomas, if the treatment/eradication of an underlying chronic inflammatory disorder/trigger factor can be excluded.
支气管相关淋巴组织淋巴瘤是一种预后良好的罕见B细胞非霍奇金淋巴瘤。我们在此报告两名有非特异性症状的患者：一名主要症状为严重血小板减少，另一名为呼吸困难和干咳，提示肺部存在炎症病灶。目前尚未确立标准治疗方案。两名患者均接受利妥昔单抗和苯达莫司汀治疗并取得成功。因此，如果可以排除潜在慢性炎症性疾病/触发因素的治疗/根除，联合免疫化疗应像其他黏膜相关淋巴组织淋巴瘤一样被视为一线治疗方案。
