巧合还是关联？一名同时患有莱恩·汉密尔顿综合征和特发性膜性肾病的患者。

Austin Scarlett, Kobrin Dale, Villgran Vipin, Nestasie Michael, Chen Feifan, Hardman Brent, Malik Khalid

Medicine Institute, Allegheny Health Network, 320 East North Avenue, Pittsburgh, PA, 15212, USA.

Division of Pulmonary and Critical Care, Allegheny Health Network, 320 East North Avenue, Pittsburgh, PA, 15212, USA.

Respir Med Case Rep. 2021 Jun 7;33:101446. doi: 10.1016/j.rmcr.2021.101446. eCollection 2021.

Lane Hamilton Syndrome is the rare association of idiopathic pulmonary hemosiderosis and Celiac Disease. The definitive pathophysiologic link is unknown, but the syndrome has been described as co-occurring along with other diseases. We describe the first reported case of Lane Hamilton Syndrome and idiopathic membranous nephropathy. We also hypothesize the possibility of an immune-mediated connection between the pathologies and propose a potential link of the phospholipase A2 receptor.

莱恩·汉密尔顿综合征是特发性肺含铁血黄素沉着症与乳糜泻的罕见关联。确切的病理生理联系尚不清楚，但该综合征已被描述为与其他疾病同时出现。我们报告了首例莱恩·汉密尔顿综合征合并特发性膜性肾病的病例。我们还推测了这些病理之间存在免疫介导联系的可能性，并提出了磷脂酶A2受体的潜在联系。