Okusaki Tai, Fukuhara Kazuhide
Department of Respiratory Medicine, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Respir Med Case Rep. 2021 Jun 26;33:101463. doi: 10.1016/j.rmcr.2021.101463. eCollection 2021.
Vaccinations against influenza viruses are widely used all over the world. There are reports, however, of some associated adverse events, and there are some case reports of interstitial lung disease occurring after influenza vaccination. We experienced the case of exacerbation of connective tissue disease-associated interstitial lung disease (CTD-ILD) after influenza vaccination, and this is the first reported case, as far as we know. The patient responded quite well to corticosteroids administration. Influenza vaccination for patients with chronic lung disease including CTD-ILD is strongly recommended, but we should be aware of possible adverse events.
流感病毒疫苗在全球广泛使用。然而，有一些关于相关不良事件的报道，也有一些流感疫苗接种后发生间质性肺病的病例报告。据我们所知，我们遇到了1例流感疫苗接种后结缔组织病相关间质性肺病（CTD-ILD）加重的病例，这是首例报道病例。该患者对皮质类固醇给药反应良好。强烈建议对包括CTD-ILD在内的慢性肺病患者接种流感疫苗，但我们应注意可能的不良事件。
