Hibino Makoto, Kondo Tetsuri
Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Japan.
Intern Med. 2017;56(2):197-201. doi: 10.2169/internalmedicine.56.7239. Epub 2017 Jan 15.
Although the influenza vaccine is relatively safe and effective, serious complications can develop in rare cases. We encountered two cases of interstitial pneumonia that developed after vaccination during the 2014-2015 influenza season. Overall, nine cases, including the two presented here, have been recorded in PubMed and the Cochrane library; eight patients were treated with corticosteroids, and all nine survived, suggesting a good prognosis. Interstitial pneumonia is rare; however, we found an increase in its incidence after 2009. Therefore, clinicians must be aware of the possibility of this complication and duly educate all patients in advance.
尽管流感疫苗相对安全有效，但在罕见情况下仍可能出现严重并发症。我们遇到了两例在2014 - 2015年流感季节接种疫苗后发生间质性肺炎的病例。总体而言，包括此处介绍的两例在内，PubMed和Cochrane图书馆共记录了9例；8例患者接受了皮质类固醇治疗，9例全部存活，提示预后良好。间质性肺炎较为罕见；然而，我们发现2009年后其发病率有所上升。因此，临床医生必须意识到这种并发症的可能性，并提前对所有患者进行适当的教育。
