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《科兴新冠疫苗接种后急性甲状腺炎和双侧视神经炎:病例报告》

Acute Thyroiditis and Bilateral Optic Neuritis following SARS-CoV-2 Vaccination with CoronaVac: A Case Report.

机构信息

Department of Ophthalmology, Suel Abujamra Institute, São Paulo, Brazil.

Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.

出版信息

Ocul Immunol Inflamm. 2021 Aug 18;29(6):1200-1206. doi: 10.1080/09273948.2021.1961815. Epub 2021 Aug 17.

Abstract

PURPOSE

To describe a case of acute thyroiditis and bilateral optic neuritis associated with SARS-CoV-2 vaccination.

METHODS

A single case report from a tertiary referral center.

RESULTS

The patient described in the following case report developed acute thyroiditis and bilateral optic neuritis following SARS-CoV-2 vaccination. The patient underwent pulse therapy followed by oral tapering corticosteroid therapy with an improvement of the bilateral disc swelling and the visual field, and recovery of thyroid-stimulating hormone to the normal limits.

CONCLUSION

Although the association between immunization and the onset of demyelinating manifestations of the central nervous system is well documented, this is the first reported case of bilateral optic neuritis and acute thyroiditis and subsequent to administration of vaccination against SARS-CoV-2.

摘要

目的

描述一例与 SARS-CoV-2 疫苗接种相关的急性甲状腺炎和双侧视神经炎病例。

方法

这是一家三级转诊中心的单一病例报告。

结果

以下病例报告中描述的患者在接种 SARS-CoV-2 疫苗后出现急性甲状腺炎和双侧视神经炎。该患者接受了脉冲治疗,随后进行了口服皮质类固醇递减治疗,双侧视盘肿胀和视野改善,促甲状腺激素恢复正常范围。

结论

尽管免疫接种与中枢神经系统脱髓鞘表现的发病之间存在关联已得到充分证实,但这是首例报告的接种 SARS-CoV-2 疫苗后发生双侧视神经炎和急性甲状腺炎的病例。

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