作为 Pyrromethene-567 染料的“点击化学”类似物的 2,6-二炔丙基取代 BODIPY 的获取：光稳定性和合成多功能性。

Access to 2,6-Dipropargylated BODIPYs as "Clickable" Congeners of Pyrromethene-567 Dye: Photostability and Synthetic Versatility.

机构信息

Instituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006, Madrid, Spain.

Departamento de Química Física. Universidad del Pais Vasco-EHU, Apartado 644, 48080, Bilbao, Spain.

出版信息

Org Lett. 2021 Sep 3;23(17):6801-6806. doi: 10.1021/acs.orglett.1c02380. Epub 2021 Aug 17.

Hitherto unreported 2,6-dipropargyl-1,3,5,7-tetramethyl BODIPYs can be efficiently prepared by a Nicholas reaction/decomplexation protocol from 1,3,5,7-tetramethyl BODIPYs. The title compounds, which improve the BODIPY photostability by retaining their inherent photophysical and photochemical properties, can be engaged in efficient copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) "click-type" reactions with azido derivatives to provide all-BODIPY-triads or conjugated BODIPYs.