Unit of Neuroepidemiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Faculty of Health and Behavioural Sciences, School of Psychology, University of Queensland, St Lucia, Australia.
Disabil Rehabil. 2022 Nov;44(22):6582-6592. doi: 10.1080/09638288.2021.1960441. Epub 2021 Aug 18.
This study aims to evaluate the effectiveness of an Acceptance and Commitment Therapy-based group resilience intervention (The REsilience and Activities for every DaY program, READY) delivered to people with MS (PwMS) frontline Italian services.
This is a single-arm longitudinal study (with a nested qualitative study). READY is composed of seven weekly in-person sessions (2.5-h each) plus a booster session five weeks later. Data were collected immediately before the program, after the booster session, and at 3-months follow-up.
Thirty-three READY groups (237 participants) were run by thirty-three trained psychologists. Participants improved in resilience (primary outcome), anxiety, depression, stress, health-related quality of life (HRQoL), and psychological flexibility and associated processes (acceptance, defusion, and values). Improvements on most outcomes occurred post-intervention and were maintained at a 3-month follow-up. No demographic or illness variables predicted these improvements. Psychological flexibility mediated improvements in resilience, anxiety, depression, stress, and HRQoL. Qualitative data confirmed READY feasibility and the positive psychological impacts on participants.
Study findings support READY effectiveness with PwMS, its broad applicability in this population, and its delivery through frontline services.IMPLICATIONS FOR REHABILITATIONREADY for MS is a highly structured, brief manualized group intervention.It is effective in improving participants' psychological functioning (resilience, anxiety, depression, stress, HRQoL, psychological flexibility, and related ACT processes).Psychological flexibility mediated the improvements in resilience, anxiety, depression, stress, HRQoL.READY can be effectively delivered through frontline services for PwMS without limitation in terms of participants' demographic and illness characteristics.
本研究旨在评估基于接纳与承诺疗法的团体韧性干预（REsilience and Activities for every DaY 方案，READY）对意大利一线服务中多发性硬化症患者（PwMS）的有效性。
这是一项单臂纵向研究（嵌套有定性研究）。READY 由七周的面对面课程（每次 2.5 小时）和五周后的强化课程组成。数据在项目开始前、强化课程后和 3 个月随访时收集。
33 名经过培训的心理学家共开展了 33 个 READY 小组（237 名参与者）。参与者的韧性（主要结局）、焦虑、抑郁、压力、健康相关生活质量（HRQoL）和心理灵活性及其相关过程（接纳、去融合和价值观）均得到改善。大多数结果在干预后得到改善，并在 3 个月随访时保持。没有人口统计学或疾病变量预测这些改善。心理灵活性中介了韧性、焦虑、抑郁、压力和 HRQoL 的改善。定性数据证实了 READY 的可行性以及对参与者的积极心理影响。
研究结果支持 READY 对 PwMS 的有效性、在该人群中的广泛适用性以及通过一线服务进行的推广。
MS READY 是一种高度结构化的、简短的手册化团体干预。它可有效改善参与者的心理功能（韧性、焦虑、抑郁、压力、HRQoL、心理灵活性和相关的 ACT 过程）。心理灵活性中介了韧性、焦虑、抑郁、压力和 HRQoL 的改善。READY 可以通过一线服务有效地提供给 PwMS，而不受参与者人口统计学和疾病特征的限制。
