Thibault L, Roberge A G
Laboratoire de Nutrition humaine et de Neurochimie, F.S.A.A., Université Laval, Québec.
Int J Vitam Nutr Res. 1987;57(4):447-52.
This study characterized the dietary pattern of 25 subjects with anorexia nervosa from a diet history. The patients mean age was 18 +/- 5 years and mean weight loss from preillness weight was 26%. Diets of anorectics were found to be significantly lower in total energy, reflecting a disturbance in nutrient intake when data were compared to a normal population. The percentage of energy derived from macronutrients was higher for protein and lower for concentrated carbohydrates, but total carbohydrates and lipids were found similar to the ones observed in normal subjects. Dietary intake of calcium, iron, thiamin, riboflavin, niacin and ascorbic acid of anorectics were significantly lower than in normal subjects. Such a particular pattern was paralleled by high serum cortisol levels and circadian cortisol cycle, low morning glycemia, high carotenemia, hypokaliemia and hyperalbuminemia. Results are discussed on the basis of the nutritional adequacy of the anorexia nervosa dietary pattern and its relationship with some aspects of the symptomatology of the disease.
本研究通过饮食史描述了25名神经性厌食症患者的饮食模式。患者的平均年龄为18±5岁，与病前体重相比平均体重减轻了26%。与正常人群的数据相比，发现神经性厌食症患者的饮食总能量显著降低，这反映出营养摄入的紊乱。宏量营养素提供的能量百分比中，蛋白质较高而精制碳水化合物较低，但总碳水化合物和脂质与正常受试者的观察值相似。神经性厌食症患者的钙、铁、硫胺素、核黄素、烟酸和抗坏血酸的饮食摄入量显著低于正常受试者。这种特殊模式与高血清皮质醇水平和昼夜皮质醇循环、低晨血糖、高胡萝卜素血症、低钾血症和高白蛋白血症同时出现。基于神经性厌食症饮食模式的营养充足性及其与该疾病某些症状学方面的关系对结果进行了讨论。
