Gwirtsman H E, Kaye W H, Curtis S R, Lyter L M
School of Medicine, University of California, Los Angeles 90024.
J Am Diet Assoc. 1989 Jan;89(1):54-7.
This study was designed to compare the dietary intakes of patients with anorexia nervosa and normal controls. Twenty-four patients hospitalized for treatment of anorexia nervosa were compared with 10 normal controls. Patients ate a self-selected diet and maintained their admission weight to within 1.0 kg during this period (19 +/- 3 days). Food chosen by each subject was weighed before and after meals, and intake was determined to be the difference. Intakes of food energy, protein, fat, and carbohydrate were calculated. Patients were closely monitored to ensure that no disposal of food occurred. Patients with anorexia nervosa had a mean daily energy intake of 1,017 +/- 54 kcal (mean +/- SEM), significantly lower than the mean energy intake for controls (1,651 +/- 108 kcal). Similarly, mean intakes of macronutrients (41 +/- 4 gm protein, 34 +/- 2 gm fat, and 136 +/- 9 gm carbohydrate) were significantly lower for patients than for controls (68.5 +/- gm protein, 65 +/- 6 gm fat, and 204 +/- 13 gm carbohydrate). However, when protein, fat, and carbohydrate were assessed as a percent of total calories, there were no significant differences between patients and controls. There were also no significant differences in calories consumed per kilogram body weight. Underweight patients with anorexia nervosa who maintain their weight on an unrestricted hospital diet have energy intake per kilogram body weight and dietary macronutrient content indistinguishable from those of normal women.
本研究旨在比较神经性厌食症患者与正常对照组的饮食摄入量。将24名因神经性厌食症住院治疗的患者与10名正常对照组进行比较。患者采用自选饮食，并在此期间（19±3天）将体重维持在入院时体重的±1.0 kg范围内。每餐前后对每个受试者所选食物进行称重，摄入量为两者之差。计算食物能量、蛋白质、脂肪和碳水化合物的摄入量。对患者进行密切监测以确保没有食物被丢弃。神经性厌食症患者的平均每日能量摄入量为1017±54千卡（平均值±标准误），显著低于对照组的平均能量摄入量（1651±108千卡）。同样，患者的常量营养素平均摄入量（蛋白质41±4克、脂肪34±2克、碳水化合物136±9克）显著低于对照组（蛋白质68.5±克、脂肪65±6克、碳水化合物204±13克）。然而，当将蛋白质、脂肪和碳水化合物按总热量的百分比进行评估时，患者与对照组之间没有显著差异。每千克体重消耗的卡路里数也没有显著差异。在无限制的医院饮食中维持体重的体重过轻的神经性厌食症患者，其每千克体重的能量摄入量和饮食常量营养素含量与正常女性没有区别。
