Beretta Mario, Maiorana Carlo, Manfredini Mattia, Signorino Fabrizio, Poli Pier Paolo, Vinci Raffaele
Implant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Via della Commenda 10, 20122 Milan, Italy.
Department of Dentistry, Vita-Salute University, IRCCS San Raffaele Hospital, 20132 Milan, Italy.
J Maxillofac Oral Surg. 2021 Sep;20(3):381-388. doi: 10.1007/s12663-020-01367-2. Epub 2020 Apr 18.
The present study evaluated the clinical and radiological stability of hard and soft tissues following alveolar socket preservation (ASP) procedure with a follow-up of 5 year from implant insertion.
The initial sample consisted of seven patients who underwent single tooth extraction and ASP procedure by means of demineralized bovine bone mineral particles covered with a porcine-derived non-cross-linked collagen matrix (CM). Each patient received a submerged single implant in the healed site. Mesial and distal peri-implant marginal bone resorption (MBR) rates were assessed radiographically at 1 year ( ) and 5 years ( ) after implant placement (baseline value).
No dropouts occurred up to 5 years. At , the MBR was 0.08 ± 0.16 mm at the mesial aspect and 0.1 ± 0.12 mm at the distal aspect. This difference was not statistically significant ( = 0.867). At , the mesial MBR was 0.15 ± 0.17 mm and the distal MBR was 0.11 ± 0.14 mm, with a non-statistically significant difference ( = 0.532). Therefore, no statistically significant differences were detected comparing mesial and distal MBR at any time point. With respect to the intra-group comparisons, no differences were observed comparing the different study periods within each variable. Indeed, the comparison between , and was non-statistically significant at both mesial ( = 0.06) and distal ( = 0.06) aspects. After 5 years, the volume of the soft tissues appeared clinically well maintained with a natural aspect around dental implants and adjacent teeth.
ASP using demineralized bovine bone mineral in combination with CM proved to be an effective technique to maintain stable dimensional volumes of both hard and soft tissues.
本研究评估了牙槽窝保存（ASP）术后硬组织和软组织的临床及影像学稳定性，并在种植体植入后进行了5年的随访。
初始样本包括7例患者，这些患者接受了单颗牙拔除及ASP手术，使用脱矿牛骨矿物质颗粒覆盖猪源非交联胶原基质（CM）。每位患者在愈合部位接受一枚潜入式单颗种植体。在种植体植入后1年（ ）和5年（ ）（基线值）时，通过影像学评估种植体近中和远中边缘骨吸收（MBR）率。
5年内无失访病例。在 时，近中MBR为0.08±0.16mm，远中MBR为0.1±0.12mm。这种差异无统计学意义（ =0.867）。在 时，近中MBR为0.15±0.17mm，远中MBR为0.11±0.14mm，差异无统计学意义（ =0.532）。因此，在任何时间点比较近中和远中MBR均未检测到统计学上的显著差异。关于组内比较，在每个变量的不同研究时期之间未观察到差异。实际上，在近中（ =0.06）和远中（ =0.06）方面， 、 和 之间的比较均无统计学意义。5年后，软组织体积在临床上保持良好，种植体及相邻牙齿周围呈现自然外观。
使用脱矿牛骨矿物质与CM联合的ASP被证明是一种维持硬组织和软组织稳定尺寸体积的有效技术。
