Qureshi Muhammad A, Syed Sofia Ali, Sharafat Shaheen
Department of Pathology, Dow International Medical College, Founding Incharge of the Dow Cancer Registry, Additional Director Dow Labs, Dow University of Health Sciences, Karachi, Pakistan.
Department of Oral Pathology, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan.
J Taibah Univ Med Sci. 2021 Mar 4;16(4):624-627. doi: 10.1016/j.jtumed.2021.02.001. eCollection 2021 Aug.
The objective of this report is to provide an overview of lip and oral cavity cancer in Karachi, the largest city in Pakistan.
This study was undertaken at the Dow Cancer Registry. During 2010-2019, all patients who were residents of Karachi who had been diagnosed with lip and oral cavity cancer were registered and recruited for this study. The data were entered in SPSS and MS Excel sheets to investigate frequencies, age-standardized-rates (ASR) and other clinicopathological parameters. The data from our study were compared with the ASR of lip and oral cavity cancer from selected Asian countries.
During the defined period, 22,858 cancer cases were registered. Of these, 4,400 (19.2%, ASR 28.0) were lip and oral cavity cancer (the most common type found in males and the second most common type in females), of which 2,986 (67.8%) were found in males, while 1,414 (32.1%) were reported in females. Squamous cell carcinoma was the most common type (97.7%). Most tumours were moderately differentiated (67.7%) followed by poorly (16.6%), and well differentiated (15.7%).
We report an alarmingly high ASR of lip and oral cavity cancer in Karachi as compared to Pakistan as a whole and other Asian countries.
本报告旨在概述巴基斯坦最大城市卡拉奇的唇癌和口腔癌情况。
本研究在陶氏癌症登记处进行。在2010年至2019年期间，所有居住在卡拉奇且被诊断为唇癌和口腔癌的患者均被登记并纳入本研究。数据录入SPSS和MS Excel表格，以调查发病率、年龄标准化率（ASR）和其他临床病理参数。我们研究的数据与选定亚洲国家唇癌和口腔癌的ASR进行了比较。
在规定期间，共登记了22,858例癌症病例。其中，4400例（19.2%，ASR 28.0）为唇癌和口腔癌（男性中最常见的类型，女性中第二常见的类型），其中2986例（67.8%）为男性，1414例（32.1%）为女性。鳞状细胞癌是最常见的类型（97.7%）。大多数肿瘤为中度分化（67.7%），其次是低分化（16.6%）和高分化（15.7%）。
我们报告称，与巴基斯坦整体及其他亚洲国家相比，卡拉奇唇癌和口腔癌的ASR高得惊人。
