Li Yanyan, Chen Yun, Xu Xuan, Tan Boyu, Liu Yingbo, Peng Xuan, Peng Danxia, Liu Shuping, Yao Jinghui
Department of Pediatric Endocrinology, Genetic Metabolism and Cardiology, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), No. 61, Liberation West Jiefang Road, Furong District, Changsha 410006, Hunan, China.
Department of Pediatric Orthopedics, Center for Orthopaedic Surgery, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, Guangdong, China.
Evid Based Complement Alternat Med. 2021 Aug 6;2021:3933854. doi: 10.1155/2021/3933854. eCollection 2021.
In recent years, children's and adolescents' growth and development issues have received increasing attention with the socioeconomic development. The etiology of child short stature involves heredity, race, sex, nutrition, and a variety of endocrine hormones, which is very complex. The age of 6∼14 is the key period of children's development. Understanding the height characteristics, the prevalence of short stature, and its influencing factors at this stage and formulating preventive measures as soon as possible are conducive to improving the average height of children and reducing the incidence of short stature. In this study, cluster sampling was used to select 56,865 children and adolescents aged 6∼14 years old from 40 primary and secondary schools in Furong District of Changsha City, and the height of each child and adolescent was measured. The results showed that the overall crude prevalence of short stature in children aged 6∼14 in Furong District of Changsha is 2.82%. Growth hormone level <10 g/L, pubertal retardation, familial short stature, low egg intake, and intrauterine growth retardation are independent risk factors affecting the occurrence of short stature. In order to improve the status quo of short stature of children aged 6∼14 in Furong District, Changsha City, targeted intervention should be strengthened for people with combined high risk factors.
近年来,随着社会经济的发展,儿童和青少年的生长发育问题受到越来越多的关注。儿童身材矮小的病因涉及遗传、种族、性别、营养以及多种内分泌激素,情况非常复杂。6至14岁是儿童发育的关键时期。了解这一阶段的身高特征、身材矮小的患病率及其影响因素,并尽早制定预防措施,有利于提高儿童的平均身高,降低身材矮小的发生率。本研究采用整群抽样的方法,从长沙市芙蓉区40所中小学选取了56865名6至14岁的儿童和青少年,并测量了每个儿童和青少年的身高。结果显示,长沙市芙蓉区6至14岁儿童身材矮小的总体粗患病率为2.82%。生长激素水平<10μg/L、青春期发育迟缓、家族性身材矮小、鸡蛋摄入量低以及宫内生长迟缓是影响身材矮小发生的独立危险因素。为改善长沙市芙蓉区6至14岁儿童身材矮小的现状,应对具有多种高危因素的人群加强针对性干预。