Kamara Mustapha Thaim Buya, Richards Veronica L, Somboonwit Charurut, Park Haesuk, Seneadza Nana Ayegua Hagan, Zhi Zhou, Jayaweera Dushyantha, Thomas Emmanuel, Cook Robert L
Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, PO Box 100231, Gainesville, FL, 32610, USA.
Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Heliyon. 2021 Aug 6;7(8):e07727. doi: 10.1016/j.heliyon.2021.e07727. eCollection 2021 Aug.
We aimed to identify disparities in self-reported HCV testing among persons living with HIV (PLWH) in Florida.
We utilized a cross-sectional study of 646 PLWH from the Florida Cohort study's baseline survey. Our analysis included chi-squared tests and logistic regression.
Participants that were 55 years old or above had more than twice the odds of reporting a past HCV test than those 18-34 years old (OR 2.47, 95% CI 1.22-5.0), which contrasted with Non-Hispanic Blacks who had lower odds of reporting a past HCV test than non-Hispanic Whites (OR 0.63, 95% CI 0.35-1.1). Drug use was also associated with higher odds of reporting a past HCV test for injection drugs (OR 2.9, 95% CI 1.0-8.43) and non-injection drugs (OR 1.52 CI 0.99-2.21). Individuals with education beyond high school had higher odds of reporting a past HCV test than those that did not attend/complete high school (OR 1.9 CI 1.11-3.16).
Our findings highlight the success of the Center for Disease Control and the U.S. Preventive Services Task Force's campaign in groups at high risk of HCV, such as baby boomers and Injection Drug Users (IDUs). However, they also reflect the current low HCV testing in PLWH that are 18-34 years old, have a low level of education, and are non-Hispanic Black. Our findings are of crucial public health significance because untreated HCV in PLWH is a major cause of severe liver disease and death. They reveal the current deficiencies in HCV testing, which is the initial step to identify underlying reasons for inadequate testing in specific groups and develop practical solutions.
我们旨在确定佛罗里达州艾滋病毒感染者（PLWH）自我报告的丙型肝炎病毒（HCV）检测差异。
我们利用了佛罗里达队列研究基线调查中646名PLWH的横断面研究。我们的分析包括卡方检验和逻辑回归。
55岁及以上的参与者报告过去进行过HCV检测的几率是18 - 34岁参与者的两倍多（比值比[OR] 2.47，95%置信区间[CI] 1.22 - 5.0），这与非西班牙裔黑人形成对比，他们报告过去进行过HCV检测的几率低于非西班牙裔白人（OR 0.63，95% CI 0.35 - 1.1）。吸毒也与注射毒品（OR 2.9，95% CI 1.0 - 8.43）和非注射毒品（OR 1.52，CI 0.99 - 2.21）报告过去进行过HCV检测的较高几率相关。高中以上学历的个体报告过去进行过HCV检测的几率高于未上过高中/未完成高中学业的个体（OR 1.9，CI 1.11 - 3.16）。
我们的研究结果凸显了疾病控制中心和美国预防服务工作组在丙型肝炎病毒高风险群体（如婴儿潮一代和注射吸毒者[IDU]）中的宣传活动取得的成功。然而，这些结果也反映出目前18 - 34岁、教育程度低且为非西班牙裔黑人的艾滋病毒感染者的丙型肝炎病毒检测率较低。我们的研究结果具有至关重要的公共卫生意义，因为艾滋病毒感染者中未治疗的丙型肝炎病毒是严重肝病和死亡的主要原因。这些结果揭示了当前丙型肝炎病毒检测方面的不足，这是确定特定群体检测不足的根本原因并制定切实可行解决方案的第一步。
