Bayat Alper Halil, Akpolat Cetin
Department of Ophthalmology, Esenler Hospital, Medipol University, Birlik Mah Bahçeler cad. no:5 Esenler 34320, Istanbul, Turkey.
Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Ther Adv Ophthalmol. 2021 Aug 10;13:25158414211034717. doi: 10.1177/25158414211034717. eCollection 2021 Jan-Dec.
The purpose of this study is to investigate the change of anterior chamber angle morphology after cataract surgery in patients with type 2 diabetes mellitus (DM2) using anterior segment optical coherence tomography (AS-OCT).
In this prospective and comparative study, 57 eyes of the patients with cataract were investigated. The patients were divided into two groups. The DM2 group included cataractous type 2 diabetic patients without diabetic retinopathy ( = 30) and the non-DM2 group included nondiabetic participants with cataract ( = 27). The AS-OCT examinations were performed at baseline and 1 month after the cataract surgery. The corrected distance visual acuity (CDVA), intraocular pressure (IOP), angle-opening distance at 500 µm (AOD-500) and trabecular iris space area at 500 µm (TISA-500), and scleral spur angle (SSA) in temporal quadrant were analyzed.
The mean age, sex, and axial length values were similar in both groups ( > 0.05 for all). The CDVA was significantly improved in both groups ( < 0.001). The mean AOD-500, TISA-500, and SSA were increased and the mean IOP was decreased after cataract surgery in both groups ( < 0.001 for all). There were not any statistically significant intergroup differences in CDVA, IOP, and AS-OCT measurements between the DM2 and non-DM2 groups ( > 0.05 for all).
Cataract surgery showed significant increases in mean anterior chamber angle parameters and reductions in IOP values in both diabetic and nondiabetic patients without intergroup significant differences. These results suggested the safety and effectiveness of cataract surgery, especially regarding anterior chamber angle parameters and so IOP changes.
本研究旨在使用眼前节光学相干断层扫描(AS-OCT)研究2型糖尿病(DM2)患者白内障手术后前房角形态的变化。
在这项前瞻性比较研究中,对57例白内障患者的眼睛进行了调查。患者分为两组。DM2组包括无糖尿病视网膜病变的2型糖尿病白内障患者(n = 30),非DM2组包括非糖尿病白内障患者(n = 27)。在基线和白内障手术后1个月进行AS-OCT检查。分析矫正远视力(CDVA)、眼压(IOP)、500μm处的房角开放距离(AOD-500)、500μm处的小梁虹膜空间面积(TISA-500)以及颞侧象限的巩膜突角(SSA)。
两组的平均年龄、性别和眼轴长度值相似(均P>0.05)。两组的CDVA均显著改善(均P<0.001)。两组白内障手术后平均AOD-500、TISA-500和SSA均增加,平均IOP降低(均P<0.001)。DM2组和非DM2组之间在CDVA、IOP和AS-OCT测量方面没有任何统计学上的显著组间差异(均P>0.05)。
白内障手术显示糖尿病和非糖尿病患者的平均前房角参数均显著增加,眼压值降低,且组间无显著差异。这些结果表明白内障手术的安全性和有效性,尤其是在前房角参数和眼压变化方面。