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犬肝胆解剖、生理和先天性疾病。

Canine hepatobiliary anatomy, physiology and congenital disorders.

机构信息

Department of Specialty Medicine, College of Veterinary Medicine, Midwestern University, Glendale, Arizona, USA.

出版信息

J Small Anim Pract. 2022 Feb;63(2):95-103. doi: 10.1111/jsap.13410. Epub 2021 Aug 18.

Abstract

The biliary system is an integral component of normal physiologic homeostasis and essential for survival. It acts as a conduit for the removal of detoxified and catabolised compounds as well as aids in fat digestion and absorption. Derangements in this system can have dangerous sequela that are associated with varying degrees of morbidity and mortality. Moreover, abnormalities in development of the biliary system can have varied and unpredictable changes on function and long-term outcome. The aims of this article were to review canine hepatobiliary anatomy, physiology and cholestasis as well as summarise congenital biliary disorders including human corollaries.

摘要

胆道系统是正常生理稳态的一个组成部分,对生存至关重要。它是一种管道,用于清除解毒和分解的化合物,并有助于脂肪消化和吸收。该系统的紊乱可能会导致严重的后果,与不同程度的发病率和死亡率相关。此外,胆道系统发育异常可能会对功能和长期结果产生不同且不可预测的变化。本文的目的是综述犬肝胆解剖、生理和胆汁淤积以及先天性胆道疾病,包括人类的相关疾病。

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