Chudakova I V, Aizenstadt T B, Rózsa K S
Institute of Developmental Biology of the Academy of Sciences of USSR, Moscow.
Acta Biol Hung. 1986;37(3-4):169-87.
Light and electron microscopic investigations were carried out on the fourth day imago of the house cricket, Acheta domestica L. treated with benserazid, or allatectomized. Introduction of benserazid (daily on the 1st, 2nd and 3rd days of imaginal life in 0.1 mg/g) failed to influence the development of the oocytes. However, benserazid in the concentration of 0.2 mg/g inhibited the growth of the terminal oocytes, while in 0.6 mg/g it completely blocked the development of terminal oocytes and vitellogenesis. The effect of benserazid proved to be reversible. Application of juvenile hormone analogue (ZR-515) prevented the effect of benserazid on the gonads of the crickets. Ultrastructural damages of the oocytes and follicular epithelium were the same in case of benserazid treatment and allatectomy, although the changes were more expressed in the latter case. The benserazid effect was found to be indirect, caused by damage to the interaction between the aminergic and peptidergic systems of the brain.
对用苄丝肼处理或已切除咽侧体的家蟋蟀（Acheta domestica L.）成虫第四天进行了光学和电子显微镜研究。在成虫期第1、2和3天每天注射0.1mg/g苄丝肼，未能影响卵母细胞的发育。然而，浓度为0.2mg/g的苄丝肼抑制了终末卵母细胞的生长，而在0.6mg/g时，它完全阻断了终末卵母细胞的发育和卵黄生成。苄丝肼的作用被证明是可逆的。施用保幼激素类似物（ZR - 515）可防止苄丝肼对蟋蟀性腺的影响。在苄丝肼处理和切除咽侧体的情况下，卵母细胞和滤泡上皮的超微结构损伤是相同的，尽管在后一种情况下变化更为明显。发现苄丝肼的作用是间接的，由脑内胺能和肽能系统之间相互作用的损伤引起。
