妊娠绵羊及其新生羔羊 中毒引起的脑病。
Encephalopathy caused by intoxication in pregnant ewes and their newborn lambs.
机构信息
Veterinary Hospital, Federal University of Campina Grande, Federal Rural University of Pernambuco, Recife, Pernambuco, Brazil.
Laboratory of Animal Diagnosis, Federal Rural University of Pernambuco, Recife, Pernambuco, Brazil.
出版信息
J Vet Diagn Invest. 2021 Nov;33(6):1128-1132. doi: 10.1177/10406387211041098. Epub 2021 Aug 25.
An outbreak of acute encephalopathy occurred in pregnant ewes and their newborn lambs associated with consumption of fruits and bark. Clinical signs in 5 adult pregnant ewes included drooling, bloat, tachypnea, depression, ataxia, body shaking, difficulty in rising, and recumbency. Three neonatal lambs born to some of those ewes had similar clinical signs. No significant gross abnormalities were observed on autopsy. Histologically, neuronal necrosis, axonal and dendritic swelling, and loss of Purkinje neurons were observed in the cerebellum. The observation of similar neurologic clinical signs and lesions in pregnant ewes and their neonatal lambs suggests that the toxic principle of crosses the placenta and reaches the fetus.
一种急性脑病在怀孕的母羊及其新生羔羊中爆发，与食用水果和树皮有关。5 只成年怀孕母羊的临床症状包括流口水、鼓气、呼吸急促、抑郁、共济失调、身体颤抖、站立困难和卧倒。其中一些母羊所生的 3 只新生羔羊也有类似的临床症状。尸检时未观察到明显的大体异常。组织学上，小脑可见神经元坏死、轴突和树突肿胀以及浦肯野神经元丢失。在怀孕的母羊及其新生羔羊中观察到类似的神经临床症状和病变表明，的毒性物质可以穿过胎盘并到达胎儿。
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