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黎巴嫩三家医院就诊儿童的铅筛查。

Lead screening in children presenting to three hospitals in Lebanon.

机构信息

Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon

Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

Arch Dis Child. 2022 Mar;107(3):251-256. doi: 10.1136/archdischild-2021-322012. Epub 2021 Aug 24.

Abstract

BACKGROUND

Lead damages most body organs and its effects are most profound in children. In a study in Beirut in 2003, before banning the leaded gasoline, 79% of the participants showed blood lead levels (BLLs) higher than 5 µg/dL. The prevalence of lead exposure in Lebanon after the ban on leaded gasoline has not been studied. This study assessed the BLL in Lebanese children aged 1-6 years.

METHODS

This cross-sectional study was conducted in three hospitals in Beirut. The children's BLLs were tested, and their caregiver completed a questionnaire to identify subgroups at risk of exposure. Participants were provided with a WHO brochure highlighting the risks of lead.

RESULTS

Ninety children with a mean age of 3.5±1.5 years were enrolled in the study and had a mean BLL of 1.1±0.7 µg/dL, with all values being below 5.0 µg/dL, showing a marked decrease in BLL compared with the mean BLL before the ban on leaded gasoline in 2002. Having a father or a mother with a college degree (p=0.01 and p=0.035, respectively) and having a monthly household income greater than $1000 (p=0.021) were associated with significantly lower BLL. Having more rooms at home and residing close to construction sites were associated with a significantly lower BLL (p=0.001 and p=0.026, respectively). Residing in a house aged >40 years and receiving traditional remedies were associated with a significantly higher BLL (p=0.009 and p<0.0001, respectively).

CONCLUSION

BLLs have declined among Lebanese children and this could be attributed to multiple factors including the ban of leaded gasoline. It would be beneficial to conduct a larger study with a nationally representative sample to better characterise the BLL.

摘要

背景

铅对大多数身体器官都有损害,对儿童的影响最为深远。2003 年在贝鲁特进行的一项研究中,在禁止使用含铅汽油之前,79%的参与者血液铅水平(BLL)高于 5μg/dL。黎巴嫩在禁止使用含铅汽油后,其儿童铅暴露的流行情况尚未得到研究。本研究评估了黎巴嫩 1-6 岁儿童的 BLL。

方法

这是一项在贝鲁特的三家医院进行的横断面研究。检测了儿童的 BLL,并让其照顾者完成一份问卷,以确定有铅暴露风险的亚组。向参与者提供了世界卫生组织的宣传册,强调了铅的风险。

结果

共有 90 名平均年龄为 3.5±1.5 岁的儿童参加了这项研究,平均 BLL 为 1.1±0.7μg/dL,所有值均低于 5.0μg/dL,与 2002 年禁止含铅汽油前的平均 BLL 相比,BLL 明显下降。父亲或母亲有大学学历(p=0.01 和 p=0.035)和家庭月收入大于 1000 美元(p=0.021)与显著较低的 BLL 相关。家中房间较多和居住地点靠近建筑工地与显著较低的 BLL 相关(p=0.001 和 p=0.026)。居住在 40 年以上的房屋和接受传统疗法与显著较高的 BLL 相关(p=0.009 和 p<0.0001)。

结论

黎巴嫩儿童的 BLL 已经下降,这可能归因于多种因素,包括禁止使用含铅汽油。进行一项具有全国代表性样本的更大规模研究将有助于更好地描述 BLL。

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