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c-Myc regulates neural stem cell quiescence and activation by coordinating the cell cycle and mitochondrial remodeling.

作者信息

Cai Chunhui, Hu Xinyu, Dai Peibin, Zhang Tianran, Jiang Mei, Wang Liefu, Hua Wanhao, Fan Yantao, Han Xin-Xin, Gao Zhengliang

机构信息

Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China.

Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.

出版信息

Signal Transduct Target Ther. 2021 Aug 25;6(1):306. doi: 10.1038/s41392-021-00664-7.

DOI:10.1038/s41392-021-00664-7
PMID:34429397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8385022/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07e4/8385022/69541e52b7cb/41392_2021_664_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07e4/8385022/69541e52b7cb/41392_2021_664_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07e4/8385022/69541e52b7cb/41392_2021_664_Fig1_HTML.jpg

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本文引用的文献

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Quiescence of Adult Mammalian Neural Stem Cells: A Highly Regulated Rest.成年哺乳动物神经干细胞的静息:高度调控的静止状态。
Neuron. 2019 Dec 4;104(5):834-848. doi: 10.1016/j.neuron.2019.09.026.
2
MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux.MYC 通过调节代谢通量控制人类多能干细胞命运决定。
Cell Stem Cell. 2017 Oct 5;21(4):502-516.e9. doi: 10.1016/j.stem.2017.08.018. Epub 2017 Sep 28.
3
Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later.成年哺乳动物神经干细胞与神经发生:五十年后
连续的转录程序是海马体干细胞激活的基础。
Sci Adv. 2025 Jun 13;11(24):eadu4523. doi: 10.1126/sciadv.adu4523. Epub 2025 Jun 11.
4
Viscoelastic N‑cadherin-like interactions maintain neural progenitor cell stemness within 3D matrices.黏弹性N-钙黏蛋白样相互作用维持神经祖细胞在三维基质中的干性。
Nat Commun. 2025 Jun 5;16(1):5213. doi: 10.1038/s41467-025-60540-8.
5
Ameliorative Effect of Moringa oleifera Against CUMS-Induced Anxiety in Rats: β-Catenin and 5-HT Crosstalk.辣木对慢性不可预知温和应激诱导的大鼠焦虑的改善作用:β-连环蛋白与5-羟色胺的相互作用
Mol Neurobiol. 2025 Apr 23. doi: 10.1007/s12035-025-04911-8.
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PTN activity in quiescent neural stem cells mediates Shank3 overexpression-induced manic behavior.静止神经干细胞中的PTN活性介导了Shank3过表达诱导的躁狂行为。
Nat Commun. 2025 Mar 11;16(1):2435. doi: 10.1038/s41467-025-57699-5.
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Brain Plasticity and Cell Competition: Immediate Early Genes Are the Focus.脑可塑性与细胞竞争:即刻早期基因是关键
Cells. 2025 Jan 19;14(2):143. doi: 10.3390/cells14020143.
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Comparison of Neurogenesis Promotion Effects between Cinnamoylquinic Acids in Neural Stem Cells from Adult Mice Brains.成年小鼠脑内神经干细胞中肉桂酰奎宁酸促进神经发生作用的比较
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