Crawford Richard, Kruger Deirdre, Moeng Maeyane
Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Trauma Unit, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa.
Ann Med Surg (Lond). 2021 Aug 10;69:102710. doi: 10.1016/j.amsu.2021.102710. eCollection 2021 Sep.
Trauma is the leading cause of morbidity and mortality worldwide with exsanguination being the primary preventable cause through early surgical intervention. We assessed two popular trauma scoring systems, injury severity scores (ISS) and shock index (SI) to determine the optimal cut off values that may predict the need for emergent surgical intervention (ESI) and in-hospital mortality.
A retrospective analysis of patient records from a tertiary hospital's trauma unit for the year 2019 was done. Descriptive statistics, univariate and multivariate logistic regression analyses were performed. Receiver operator characteristic (ROC) curve analysis was conducted and area under the curve (AUC) reported for predicting the need for ESI in all study participants, as well as in patients with penetrating injuries alone, based on continuous variables of ISS, SI or a combination of ISS and SI. The Youdin Index was applied to determine the optimal ISS and SI cut off values.
A total of 1964 patients' records were included, 89.0% were male and the median age (IQR) was 30 (26-37) years. Penetrating injuries accounted for 65.9% of all injuries. ISS and SI were higher in the ESI group with median (IQR) 11 (10-17) and 0.74 (0.60-0.95), respectively. The overall mortality rate was 4.5%. The optimal cut-off values for ESI and mortality by ISS (AUC) were 9 (0.74) and 12 (0.86) (p = 0.0001), with optimal values for SI (AUC) being 0.72 (0.60), and 0.91 (0.68) (p = 0.0001), respectively.
ISS and SI are significant, independent prognosticators for the need of ESI and in-hospital mortality.
创伤是全球发病和死亡的主要原因,而出血是通过早期手术干预可预防的主要原因。我们评估了两种常用的创伤评分系统,即损伤严重程度评分(ISS)和休克指数(SI),以确定可预测紧急手术干预(ESI)需求和院内死亡率的最佳临界值。
对一家三级医院创伤科2019年的患者记录进行回顾性分析。进行描述性统计、单变量和多变量逻辑回归分析。基于ISS、SI或ISS与SI的组合等连续变量,进行受试者操作特征(ROC)曲线分析,并报告曲线下面积(AUC),以预测所有研究参与者以及仅穿透伤患者对ESI的需求。应用尤登指数确定最佳的ISS和SI临界值。
共纳入1964例患者记录,89.0%为男性,中位年龄(四分位间距)为30(26 - 37)岁。穿透伤占所有损伤的65.9%。ESI组的ISS和SI较高,中位数(四分位间距)分别为11(10 - 17)和0.74(0.60 - 0.95)。总体死亡率为4.5%。ESI和死亡率的ISS(AUC)最佳临界值分别为9(0.74)和12(0.86)(p = 0.0001),SI(AUC)的最佳值分别为0.72(0.60)和0.91(0.68)(p = 0.0001)。
ISS和SI是ESI需求和院内死亡率的重要独立预测指标。